1654Cell155,December19,2013©2013ElsevierInc.DOIhttp://dx.doi.org/10.1016/j.cell.2013.12.005Seeonlineversionforlegendandreferences.SnapShot:LipidKinasesandPhosphatasesSimonA.RudgeandMichaelJ.O.WakelamTheBabrahamInstitute,BabrahamResearchCampus,CambridgeCB223AT,UKGeneReaction(s)catalyzedinvitroReaction(s)catalyzedinvivoPIK3C3PI→PI(3)PPI→PI(3)PPIK3C2API→PI(3)P,PI(4)P→PI(3,4)P2,PI(4,5)P2→PI(3,4,5)P3PI→PI(3)P,PI(4)P→PI(3,4)P2PIK3C2BPI→PI(3)P,PI(4)P→PI(3,4)P2,PI(4,5)P2→PI(3,4,5)P3PI→PI(3)PPIK3C2GPI→PI(3)P,PI(4)P→PI(3,4)P2_PIKFYVEPI→PI(5)P,PI(3)P→PI(3,5)P2PI→PI(5)P,PI(3)P→PI(3,5)P2PIP4K2API(3)P→PI(3,4)P2→PI(3,4,5)P3,PI(5)P→PI(4,5)P2PI(5)P→PI(4,5)P2PIP4K2BPI(3)P→PI(3,4)P2,PI(5)P→PI(4,5)P2PI(5)P→PI(4,5)P2PIP4K2CPI(5)P→PI(4,5)P2_PIK3CAPI→PI(3)P,PI(4)P→PI(3,4)P2,PI(4,5)P2→PI(3,4,5)P3PI(4,5)P2→PI(3,4,5)P3PIK3CBPI→PI(3)P,PI(4)P→PI(3,4)P2,PI(4,5)P2→PI(3,4,5)P3PI(4,5)P2→PI(3,4,5)P3PIK3CDPI→PI(3)P,PI(4)P→PI(3,4)P2,PI(4,5)P2→PI(3,4,5)P3PI(4,5)P2→PI(3,4,5)P3PIK3CGPI→PI(3)P,PI(4)P→PI(3,4)P2,PI(4,5)P2→PI(3,4,5)P3PI(4,5)P2→PI(3,4,5)P3IPMKPI(4,5)P2→PI(3,4,5)P3PI(4,5)P2→PI(3,4,5)P3PIP5K1API→PI(5)P,PI(3)P→PI(3,4)P2→PI(3,4,5)P3,PI(3)P→PI(3,5)P2,PI(4)P→PI(4,5)P2,PI(3,4)P2→PI(3,4,5)P3PI(4)P→PI(4,5)P2PIP5K1BPI→PI(5)P,PI(3)P→PI(3,4)P2→PI(3,4,5)P3,PI(3)P→PI(3,5)P2,PI(4)P→PI(4,5)P2,PI(3,4)P2→PI(3,4,5)P3PI(4)P→PI(4,5)P2PIP5K1CPI(3)P→PI(3,4)P2→PI(3,4,5)P3,PI(3)P→PI(3,5)P2,PI(4)P→PI(4,5)P2,PI(3,4)P2→PI(3,4,5)P3PI(4)P→PI(4,5)P2PI4K2API→PI(4)PPI→PI(4)PPI4K2BPI→PI(4)PPI→PI(4)PPI4KAPI→PI(4)PPI→PI(4)PPI4KBPI→PI(4)PPI→PI(4)PMTM1PI(3)P→PI,PI(3,5)P2→PI(5)PPI(3)P→PI,PI(3,5)P2→PI(5)PMTMR1PI(3)P→PI,PI(3,5)P2→PI(5)P_MTMR2PI(3)P→PI,PI(3,5)P2→PI(5)PPI(3)P→PIMTMR3PI(3)P→PI,PI(3,5)P2→PI(5)PPI(3,5)P2→PI(5)PMTMR4PI(3)P→PIPI(3)P→PIMTMR6PI(3)P→PI,PI(3,5)P2→PI(5)PPI(3,5)P2→PI(5)PMTMR7PI(3)P→PI_MTMR8PI(3)P→PI,PI(3,5)P2→PI(5)PPI(3)P→PIMTMR14PI(3)P→PI,PI(3,5)P2→PI(5)PPI(3)P→PI,PI(3,5)P2→PI(5)PPTENPI(3)P→PI,PI(3,4)P2→PI(4)P...
