Seeonlineversionforlegendandreferences.1160Cell137,June12,2009©2009ElsevierInc.DOI10.1016/j.cell.2009.05.039SnapShot:FBoxProteinsIJeffreyR.Skaar,1JuliaK.Pagan,1andMichelePagano1,21NYUSchoolofMedicineand2HowardHughesMedicalInstitute,NewYork,NY10016,USAD.melanogasterfBoxProteinsubstrateBiologicalfunctionsofsubstratesororphanfBoxProteinskinase(s)AgoTrhtxnfactor,tracheadevelopmentCycEcyclin,cellcycleCdk2dMyctxnfactor,cellgrowth/proliferationNotchtransmembranereceptor,NotchsignalingSlimbARMtxnactivator,WinglesspathwaySggCitxnfactor,HedgehogsignalingCK1Cacttxnfactor,NF-κBsignalingDltxnfactor,NF-κBsignalingE2Ftxnfactor,cellcyclePERtxnactivator,circadianrhythmsDbtPLK4kinase,cellcycleReltxnfactor,NF-κBsignalingCG11033/dKdm2histoneH2AcorehistonecomponentCG13213/Fbl6Yantxnfactor,cellgrowth/proliferationFbxl4unknowncalciumsignalingJetlagTimtxnactivator,circadianrhythmsPpaPrdhomeoboxtxnfactor,developmentCG4643/dFsnWndkinase,synapticgrowthMorgueTh/DIAP1Ubligase,inhibitorofapoptosisPallunknownphagocytosisofapoptoticcellsRca1unknownAPC/CinhibitorS.cerevisiaefBoxProteinsubstrateBiologicalfunctionsofsubstratesororphanfBoxProteinskinase(s)Cdc4pCdc6ppre-RCcomponent,DNAreplicationCdc28pClb6pB-typecyclin,cellcycleCdc28p,Pho85pCtf13pCBF3complexmember,chromosomecohesionFar1pCDKinhibitor,cellcycle,pheromonepathwayCdc28pGcn4ptxnfactor,aminoacidsynthesisPho85p,Srb10Gis4pRAS/cAMPsignalingHac1ptxnfactor,unfoldedproteinresponseRcn1pcalcineurinregulation,calciumsignalingMck1pSic1pCDKinhibitor,cellcycleCdc28pSwi5ptxnfactor,cellcycleTec1ptxnfactor,filamentationpathwayFus3pMet30pFzo1pintegralmembrane,mitochondrialfusionMet4ptxnactivator,sulfuraminoacidsynthesisSwe1kinase,Cdkinhibitor,cellcycleAmn1punknownmitoticexitnetworkCtf13punknowncentromeric/chromosomecohesionDia2punknownDNAreplicationGrr1pAro1paromaticaminoacidsynthesisCln1pG1cyclin,cellcycleCdc28pCln2pG1cyclin,cellcycleCdc28pGal2pgalactosepermease,galactosepathwayGal4ptxnfactor,galactosepathwayGic2pactincytoskeletonregulationCdc28pHis4...
