EmergingStrategiesofCancerTherapyBasedonFerroptosisDr.ZheyuShen,CASKeyLaboratoryofMagneticMaterialsandDevices,&KeyLaboratoryofAdditiveManufacturingMaterialsofZhejiangProvince,&DivisionofFunctionalMaterialsandNanodevices,NingboInstituteofMaterialsTechnologyandEngineering,ChineseAcademyofSciences,1219ZhongGuanWestRoad,Ningbo,Zhejiang315201,China,aiguo@nimte.ac.cn,LaboratoryofMolecularImagingandNanomedicine,NationalInstituteofBiomedicalImagingandBioengineering,NationalInstitutesofHealth,Bethesda,Maryland20892,UnitedStates,shawn.chen@nih.gov;zijian.zhou@nih.govDr.JibinSong,LaboratoryofMolecularImagingandNanomedicine,NationalInstituteofBiomedicalImagingandBioengineering,NationalInstitutesofHealth,Bethesda,Maryland20892,UnitedStates,shawn.chen@nih.gov;zijian.zhou@nih.govDr.BryantC.Yung,LaboratoryofMolecularImagingandNanomedicine,NationalInstituteofBiomedicalImagingandBioengineering,NationalInstitutesofHealth,Bethesda,Maryland20892,UnitedStates,shawn.chen@nih.gov;zijian.zhou@nih.govDr.ZijianZhou*,LaboratoryofMolecularImagingandNanomedicine,NationalInstituteofBiomedicalImagingandBioengineering,NationalInstitutesofHealth,Bethesda,Maryland20892,UnitedStates,shawn.chen@nih.gov;zijian.zhou@nih.govProf.AiguoWu*,andCASKeyLaboratoryofMagneticMaterialsandDevices,&KeyLaboratoryofAdditiveManufacturingMaterialsofZhejiangProvince,&DivisionofFunctionalMaterialsandNanodevices,NingboInstituteofMaterialsTechnologyandEngineering,ChineseAcademyofSciences,1219ZhongGuanWestRoad,Ningbo,Zhejiang315201,China,aiguo@nimte.ac.cnProf.XiaoyuanChen*LaboratoryofMolecularImagingandNanomedicine,NationalInstituteofBiomedicalImagingandBioengineering,NationalInstitutesofHealth,Bethesda,Maryland20892,UnitedStates,shawn.chen@nih.gov;zijian.zhou@nih.govAbstractFerroptosis,anewformofregulatedcelldeaththatisiron-andreactiveoxygenspecies(ROS)-dependent,hasattractedmuchattentionintheresearchcommunitiesofbiochemistry,oncology,andespeciallythematerialsciences.SincethefirstdemonstrationbyStockwelletal.in2012,aserie...