InsightReportBiosecurityInnovationandRiskReduction:AGlobalFrameworkforAccessible,SafeandSecureDNASynthesisJanuary2020IncollaborationwiththeNuclearThreatInitiative(NTI)PrefaceForewordIntroductionExecutivesummaryDevelopingacommonDNAsequencescreeningmechanismOversight,policiesandpartnershipsforestablishingsyntheticDNAscreeningasaglobalnormConclusionAppendicesContributorsWorldEconomicForum91-93routedelaCapiteCH-1223Cologny/GenevaSwitzerlandTel.:+41(0)228691212Fax:+41(0)227862744Email:contact@weforum.orgwww.weforum.org©2019WorldEconomicForum.Allrightsreserved.Nopartofthispublicationmaybereproducedortransmittedinanyformorbyanymeans,includingphotocopyingandrecording,orbyanyinformationstorageandretrievalsystem.Contents34568111314173BiosecurityInnovationandRiskReduction:AGlobalFrameworkforAccessible,SafeandSecureDNASynthesisPrefaceTheFourthIndustrialRevolutiondescribesaworldwherenewtechnologiesandapproachesaremergingthephysical,digitalandbiologicalworldsinwaysthatstandtotransformsociety.Ensuringthatthistransformationispositivewilldependonhowtherisksandopportunitiesthatarisealongthewayarenavigated.BiotechnologyisatthecentreoftheFourthIndustrialRevolution.Todeliveronthepromiseofthebiotechnologyrevolution,wemustseizeopportunitiestodevelopanddeliverlife-advancinginnovationswhilesimultaneouslyandurgentlyaddressingpotentialrisksassociatedwithagrowinganddemocratizedbioeconomy.Throughouttheprocessofdevelopingitsrecommendations,theWorkingGrouprecalledthattheinternetwasbuiltwithoutcybersecurityinmind.Thesamechoicenowliesbeforeus,atthebeginningofthebiotechnologyrevolution.ItisacredittotheWorkingGroupthat,asthebiotechnologyrevolutioniscreatingundreamed-ofpossibilitiesforinnovationandindustrialization,dueconsiderationisgiventomanagingrisksothatthechancetobuildthebiotechnologyrevolutionwithbiosecurityinmindisnotmissed.ArnaudBernaertHeadofShapingtheFutureofHealthandHealthcareWorldEconomicForum4BiosecurityInnovationandRiskReduction:AGlobalFrameworkforAccessible,SafeandSecureDNASynthesis...