TECHFACTSHEETSFORPOLICYMAKERSFALL2020SERIESVaccinePlatformsAUTHORSTessCushing(Harvard)AmrithaJayantiREVIEWERSAmeshAdalja,Ph.D.(JohnsHopkins)GalitAlter,Ph.D.(Harvard)AaronSchmidt,Ph.D.(Harvard)ASHCARTER,TAPPFACULTYDIRECTORLAURAMANLEY,TAPPDIRECTORTECHNOLOGYANDPUBLICPURPOSEPROJECTTheTechnologyFactsheetSerieswasdesignedtoprovideabriefoverviewofeachtechnologyandrelatedpolicyconsiderations.Thesepapersarenotmeanttobeexhaustive.TechnologyandPublicPurposeProjectBelferCenterforScienceandInternationalAffairsHarvardKennedySchool79JohnF.KennedyStreet,Cambridge,MA02138www.belfercenter.org/TAPPStatementsandviewsexpressedinthispublicationaresolelythoseoftheauthorsanddonotimplyendorsementbyHarvardUniversity,HarvardKennedySchool,theBelferCenterforScienceandInternationalAffairs.DesignandlayoutbyAndrewFaciniCopyright2021,PresidentandFellowsofHarvardCollegePrintedintheUnitedStatesofAmericaTECHPOLICYFACTSHEET:VACCINEPLATFORMS|BELFERCENTERFORSCIENCEANDINTERNATIONALAFFAIRS1ExecutiveSummary1Shere,Jack,A.“VeterinaryServicesMemorandum800.213.”UnitedStatesDepartmentofAgriculture,2015.AvailableOnline.https://www.aphis.usda.gov/animal_health/vet_biologics/publications/memo_800_213.pdf2WorldhealthOrganizationExpertCommitteeonBiologicalStandardization.“Guidelinesonthequality,safety,andefficacyofrespiratorysyncytialvirusvaccines.”November,2019.Availableonline.https://www.who.int/biologicals/expert_committee/RSV_Guidelines_POST_ECBS.PDF?ua=13https://www.centerforhealthsecurity.org/our-work/pubs_archive/pubs-pdfs/2019/190423-OPP-platform-report.pdf4Ibid.Avaccineplatformisa“plug-and-play”physicalframeworkthatcanbeusedwhendevelopingvaccinesforemerginginfectiousdiseases,suchasCOVID-19.Vaccineplatformsuseabasecarrieror“vehicle,”suchasanucleicacid,viralvector,orliposome,whichcanbeusedinterchangeablyforvariousdiseases.Oncedesignedandlicensedforonevaccine,thedevelopmentoffuturevaccinesusingthesameplatformwouldsimplyrequiresubstitutingthedesiredantigeniccomponent,orageneticcompoundthatnormal-lytri...
