第36卷第3期2023年6月华夏医学ActaMedicinaeSinicaVol.36No.3Jun.2023DOI:10.19296/j.cnki.1008-2409.2023-03-017·临床研究··CLINICALRESEARCH·Rh血型系统抗原检测在受血者输血治疗中的应用效果①王艳琴②(江西省中西医结合医院,江西南昌330003)摘要目的:探讨Rh血型系统抗原检测在精准输血中的价值。方法:94例需输血治疗的患者分为对照组和观察组,每组47例。受血者E抗原阴性、供血者E抗原阳性为对照组;受血者、供血者E抗原均为阴性者为观察组。分析两组免疫功能指标、不良反应。结果:对照组输血后第3天的免疫球蛋白M(IgM)水平高于输血前,CD+3细胞、CD+4细胞占比低于输血前;对照组输血后第3天的IgM、白介素-2(IL-2)水平高于观察组,CD+3细胞、CD+4细胞占比低于观察组,差异有统计学意义(P<0.05);对照组不良反应发生率17.02%高于观察组6.26%(P<0.05)。结论:基于Rh血型系统抗原检测的精确输血可减少输血对机体免疫系统的干扰,降低输血不良反应发生风险。关键词:Rh血型;抗原检测;精准输血中图分类号:R446.11文献标志码:A文章编号:1008-2409(2023)03-0086-04ApplicationeffectsofRhbloodgroupsystemantigendetectiononbloodtransfusiontherapyforrecipients①WANGYanqin②(JiangxiIntegratedTraditionalChineseandWesternMedicineHospital,Nanchang330003,China)AbstractObjective:ToexplorethevalueofRhbloodgroupsystemantigendetectioninaccuratebloodtransfusion.Methods:94patientsrequiringbloodtransfusiontreatmentwereselectedfromthehospital,with47casesineachgroup.TherecipientswithnegativeEantigenandthedonorswithpositiveEantigenwereservedasthecontrolgroup.TherecipientsanddonorswithnegativeEantigenwereservedastheobservationgroup.Theimmunefunctionindexesandadversereactionswerecomparedbetweenthetwogroups.Results:Threedaysafterbloodtransfusion,thelevelsofimmunoglobulinM(IgM)inthecontrolgroupwerehigherthanthosebeforebloodtransfusion,andtheproportionofCD+3andCD+4werelowerthanthosebeforebloodtransfusion.Threedaysafterbloodtransfusion,thelevelsofIgMandIL-2inthecontrolgroupwerehigherthanthoseintheobservationgroup,andthelevelsofCD+3andCD+4werelowerthan·68·①基金项目:江西省卫生计生委科技计划项目(20177026)。②作者简介:王艳琴,本科,副主任技师,研究方向为输血。E-mail:wyanqinan@163.co...
