（临床研究）·论著·:1069.临床医学工程2023年8月第30卷第8期丙酸氟替卡松联合孟鲁司特钠治疗慢性咳嗽患儿的临床效果及其对CRP、IgE水平的影响聂钊，石海莎（河南省直第三人民医院儿科，河南郑州450006)【摘要】】目的探讨丙酸氟替卡松联合孟鲁司特钠治疗慢性咳嗽患儿的临床效果及对C反应蛋白（CRP）、免疫球蛋白E（IgE）水平的影响。方法86例慢性咳嗽患儿随机分为两组，对照组采用孟鲁司特钠治疗，观察组采用孟鲁司特钠联合丙酸氟替卡松治疗，比较两组的治疗效果及治疗前后的CRP、IgE水平。结果观察组的治疗总有效率为90.70%，显著高于对照组的74.42%（P<0.05）。治疗后，两组的CRP、IgE水平均显著低于治疗前，且观察组的CRP、IgE水平均显著低于对照组（P<0.05)。结论丙酸氟替卡松联合孟鲁司特钠治疗慢性咳嗽患儿的临床效果显著，可降低患儿CRP、IgE水平。【关键词】慢性咳嗽；丙酸氟替卡松；孟鲁司特钠；临床疗效；C反应蛋白；免疫球蛋白E中图分类号：R725.6文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.08.1069ClinicalEffectofFluticasonePropionateCombinedwithMontelukastSodiumintheTreatmentofChildrenwithChronicCoughandItsImpactonCRPandIgELevels//NIEZhao,SHIHaisha(DepartmentofPediatrics,He'nanProvincialThirdPeople'sHospital,Zhengzhou450006,China)[Abstract]ObjectiveToexploretheclinicaleffectoffluticasonepropionatecombinedwithmontelukastsodiuminthetreatmentofchildrenwithchroniccoughanditsimpactonC-reactiveprotein(CRP)andimmunoglobulinE(IgE)levels.Methods86childrenwithchroniccoughwererandomlydividedintotwogroups.Thecontrolgroupwastreatedwithmontelukastsodium,andtheobservationgroupwastreatedwithmontelukastsodiumcombinedwithfluticasonepropionate.ThetherapeuticeffectandthelevelsofCRPandIgEbeforeandaftertreatmentwerecomparedbetweenthetwogroups.ResultsThetotaleffectiverateoftreatmentintheobservationgroupwas90.70%,significantlyhigherthan74.42%inthecontrolgroup(P<0.05).Aftertreatment,thelevelsofCRPandIgEinthetwogroupsweresignificantlylowerthanthosebeforetreatment,andthelevelsofCRPandIgEintheobservationgroupweresignificantlylowerthanthoseinthecontrolgroup(P<0.05).ConclusionsFluticasonepropionatecombinedwithmontelukastsodiuminthetreatmentofchild...
