传染病信息2023年6月30日第36卷第3期InfectDisInfo,Vol.36,No.3,June30,2023·278·超声造影剂注射用六氟化硫微泡致过敏性休克1例彭宇辉,苏海滨,冯卉,赵乐,李晨[摘要]1例59岁男性乙型肝炎肝硬化患者为明确肝占位性病变性质行肝脏超声造影检查,静脉推注六氟化硫微泡约20s后,患者出现表情淡漠、焦躁不安、血压下降、乳酸增高等表现,考虑为造影剂导致的过敏性休克。立即停用该药,迅速给予抗过敏、抗休克、补液、扩容等治疗,38min后患者过敏性休克症状明显缓解,生命体征恢复正常。[关键词]乙型肝炎肝硬化;肝占位性病变;诊断;六氟化硫微泡;临床表现;过敏性休克;药物相关副作用和不良反应[中国图书资料分类号]R51[文献标志码]A[文章编号]1007-8134(2023)03-0278-03DOI:10.3969/j.issn.1007-8134.2023.03.017AcaseofanaphylacticshockcausedbyultrasoundcontrastagentsulfurhexafluoridemicrobubblesforinjectionPengYuhui,SuHaibin,FengHui,ZhaoLe,LiChen*DepartmentofHepatology,SeniorDepartmentofHepatology,theFifthMedicalCenterofPLAGeneralHospital,Beijing100039,China*Correspondingauthor,E-mail:gemini_lee525@126.com[Abstract]Toclarifythenatureofthehepaticspace-occupyinglesions,a59-year-oldmalepatientwithhepatitisBvirusrelatedcirrhosisunderwentlivercontrast-enhancedultrasonography.About20safterintravenousinjectionofsulfurhexafluoridemicrobubbles,thepatientshowedapathy,restlessness,decreasedbloodpressureandincreasedlacticacid,whichwasconsideredtobeanaphylacticshockcausedbycontrastagents.Westopthedrugimmediately,andgiveanti-allergy,anti-shock,fluidreplacementandvolumeexpansiontreatmentsquickly.After38minutes,thesymptomsofanaphylacticshockofthepatientweresignificantlyrelieved,andhisvitalsignsreturnedtonormal.[Keywords]HepatitisBcirrhosis;spaceoccupyinglesionofliver;diagnosis;sulfurhexafluoridemicrobubbles;clinicalmanifestation;anaphylacticshock;drug-relatedsideeffectandadversereactions[作者单位]100039北京,解放军总医院第五医学中心肝病医学部肝病科(彭宇辉、苏海滨、李晨),心超声科(冯卉);030000太原,山西医科大学第一医院妇科(赵乐)[通信作者]李晨,E_mail:gemini_lee525@126.com1临床资料患者,男,59岁,身高166cm,体重75kg,主因上腹...