临床医学研究与实践2023年3月第8卷第9期EffectofcognitivebehavioraltherapycombinedwithdrugsinthetreatmentofirritablebowelsyndromeanditsinfluencesonanxietyanddepressionofpatientsJIYongsheng,SHENXuehui,CHENQian,PANJuhua,YANGJin(DigestiveMedicineDepartment,QidongHospitalofTCM,Qidong226200,China)ABSTRACT:ObjectiveToexploretheeffectofcognitivebehavioraltherapy(CBT)combinedwithdrugsinthetreatmentofirritablebowelsyndrome(IBS)anditsinfluencesonanxietyanddepressionofpatients.MethodsAtotalof96patientswithIBSadmittedinthedigestivemedicineclinicofourhospitalfromJanuary2020toJune2022wereselectedastheresearchobjectsanddividedintocontrolgroupandobservationgroupaccordingtotherandomnumbertablemethod,with48casesineachgroup.Thecontrolgroupwasgivendrugstreatment,andtheobservationgroupwasgivenCBTtreatmentonthebasisofthecontrolgroup.Thesymptomsimprovementtime,IBSSymptomSeverityScale(IBS-SSS)andIBSQualityofLifeScale(IBS-QOL)scores,clinicalefficacy,anxiety,depressionandrecurrenceratewerecomparedbetweenthetwogroups.ResultsTheimprovementtimeofabdominalpain,abdominaldistension,abdominaldiscomfortandabnormaldefecationintheobservationgroupwereshorterthanthoseinthecontrolgroup,andthedifferenceswerestatisticallysignificant(P<0.05).Beforetreatment,therewerenosignificantdifferencesinIBS-SSSandIBS-QOLscoresbetweenthetwogroups(P>0.05);aftertreatment,theIBS-SSSandIBS-QOLscoresofthetwogroupsdecreased,thoseintheobservationgroupwerelowerthanthecontrolgroup,andthedifferenceswerestatisticallysignificant(P<0.05).Thetotaleffectiverateoftreatmentintheobservationgroupwas93.75%,whichwashigherthan79.17%inthecontrolgroup,andthedifferencewasstatisticallysignificant(P<0.05).Beforetreatment,therewerenosignificantdifferencesinthescoresofSelf-RatingAnxietyScale(SAS)andSelf-RatingDepressionScale(SDS)betweenthetwogroups(P>0.05);aftertreatment,thescoresofSASandSDSinthetwogroupsdecreased,thoseintheobservationgroupwerelowerthanthecontrolgroup,andthedifferenceswerestatisticallysignificant(P<0.05).Therecurrencerateoftheobser...
