乙肝两对半的解读Secondliverhalf-and-halhinterpretatino第一页，共十四页。•乙肝两对半的定义TheDefinitinoOfSecongLiverTwoHalf-and-Half•大三阳和小三阳Big3thisworldandsmall3thisworld•乙肝的传播途径Thetransmissionwayofsecondliver*对乙肝的误解Misunderstandingofhepatitisb第二页，共十四页。什么是乙肝两对半•乙肝两对半是国内医院最常用的乙肝病毒(HBV)感染检测血清标志物。•(Secondlivertwohalf-and-halfisthemostcommonlyusedindomestichospitalofhepatitisbvirus(HBV)infectiondetectionserummarker)•①乙肝外表抗原〔HBsAg〕•②乙肝外表抗体〔抗-HBs〕•③乙肝e抗原〔HBeAg〕•④乙肝e抗体〔抗-HBe〕•⑤乙肝核心抗体〔抗-HBc〕测定两种抗原和三种抗体，也就是俗称的“两对半〞。Determinationoftwokindsofantigensandthreekindsofantibody,alsoknownasthe"twohalf-and-half".第三页，共十四页。大三阳和小三阳Big3thisworldandsmall3thisworld•“大三阳〞是指“乙肝两对半〞化验结果为外表抗原、e抗原和核心抗体检测均是阳性。一般说明病毒复制水平高、传染性强。•"Big3thisworld"refersto"secondlivertwohalf-and-half"testresultsforthesurfaceantigen,eantigenandcoreantibodytestsarepositive.Generaldescriptionswithhigh-levelviralreplicationandinfectivity.•“小三阳〞是指“乙肝两对半〞化验结果为外表抗原、E抗体和核心抗体检测均是阳性。一般说明病毒复制水平相对较低、传染弱。•Whatissmall3thisworld"small3thisworld"refersto"secondlivertwohalf-and-half"testresultsforthesurfaceantigen,Eantibodyandcoreantibodytestsarepositive.Generaldescriptionsviralreplicationlevelisrelativelylowandweak.可见大三阳和小三阳的区别主要在病毒复制活泼程度上，但并不表示“大三阳〞一定比“小三阳〞病情严重，临床研究证实，有些小三阳患者更容易转化为肝癌。在治疗上，如果是乙肝患者且HBVDNA含量高，大三阳和小三阳的区别不大，都要以抗病毒治疗为主，辅助抗炎保肝，抗纤维化治疗。Visiblebig3thisworldandsmall3thisworlddifferenceismainlyintheviralreplicationactivity,butitdoesn'tmeanthe"big3thisworld"than"small3thisworld"thediseaseissevere,clinicalstudieshaveconfirmedthatsomesmall3thisworldaremorelikelytobeconvertedintolivercancerpatients.Intreatment,ifishepatitisbpatientsand...
