2022年医学专题—肝性脑病英文PPT.pptVIP免费

HepaticEncephalopathy（HE）DongXuan第一页，共二十页。PartsDefinitionCausesHypothesisSymptomsandSignsExaminationsTreatment第二页，共二十页。severeliverdiseases.metabolicdisordercentralnervoussystemdisordermainclinicalsymptomsdisturbanceofconsciousnessbehaviordisordercomapoints第三页，共二十页。DefinitionHEisacomplex,potentiallyreversibledisturbanceincentralnervoussystemthatoccursasaconsequenceofsevereliverdiseases.第四页，共二十页。CausesMainCirrhosisSeverehepatitisFulminantliverfailureSeverebiliaryinfectionAcutefattyliverofpregnancyperiod70%causedbycirrhosis第五页，共二十页。PrecipitatingfactorsofHE1)GastrointestinalBleeding2)Abuseofsedativesandnarcotic3)Massiveparacentesisandexcessivediuresis4)InfectionsHypovolemia,shock,hypoxiaProteinbreakdownAmmoniaproductionbenzodiazepinesandbarbituratesFluidorelectrolyteabnormalitiesandacidbasedisturbancetissuebreakdown第六页，共二十页。SeveralmainhypothesesAmmoniaIntoxicationFalseNeurotransmittersAminoAcidimbalanceTheGamma-AminobutyricAcidhypothesis第七页，共二十页。Symptoms1.(prodromalstage)Slightlyalteredmoodorbehaviors2.(precomastage)Somnipathyandinappropriatebehaviors3.(lethargicstage)Drowsyandpsychopath4.(comastage)DeepcomacentralnervoussystemFourstagesofhepaticencephalopathy第八页，共二十页。第九页，共二十页。FlappingtremorA.PatientB.Doctorandpatient第十页，共二十页。ClassificationLevelMentalStatusFlappingtremorⅠSlightlyWeakpositiveⅡSomnipathyandPositiveinappropriateⅢDrowsyandPositivepsychopathⅣDeepcomaNegative第十一页，共二十页。Examinations1)Bloodammoniachronic()acute()2)EEGslowsmallvalue3)PsychometrictestAdvantages:simple,noequipmentDisadvantage:influencedbyageandeducation第十二页，共二十页。Numberconnectiontest第十三页，共二十页。Graphicsconnectiontest第十四页，共二十页。Imagingexamination(CTorMRI)AcuteHE:CerebraledemaChronicHE:Encephalatrophy第十五页，共二十页。Criticalfricker-fusionfrequencyThroughtestingtheretinalglialcelllesiontojudgethebrainastrocyteshaveswellingAdvantages:sensitive,simpleandreliable第十六页，共二十页。TreatmentPrinciples1）Eliminatingorcorrectingprecipitatingfactors2）Reducingplasmaammoniaandothertoxin3）Correctingplasmaaminoacidimbalanceandsupplyingnormalneurotransmitters第十七页，共二十页。4)Improvinghepatocytefunctions5)Livertransplantation第十八页，共二十页。Thankyou第十九页，共二十页。内容(nèiróng)总结HepaticEncephalopathy（HE）。1)GastrointestinalBleeding。Hypovolemia,shock,hypoxia。TheGamma-Aminobutyric。Criticalfricker-fusionfrequency。5)Livertransplantation。you第二十页，共二十页。