•OrganicnitratesOrganicnitrates•receptorblockersreceptorblockers第一页，共三十一页。Coronaryvessels:Coronaryvessels:bloodsupplyfortheheartbloodsupplyfortheheart1.OVERVIEW1.OVERVIEW第二页，共三十一页。Coronaryatherosclerosis:Coronaryatherosclerosis:causeofcardiacischemiacauseofcardiacischemia第三页，共三十一页。DistributionofcoronaryarteriesintheheartDistributionofcoronaryarteriesintheheart第四页，共三十一页。Ischemia(Ischemia(anginapectorisanginapectoris):):imbalancebetweenoxygendemandandsupplyimbalancebetweenoxygendemandandsupply第五页，共三十一页。Classificationofanginapectoris:Classificationofanginapectoris:Exertionalangina(Exertionalangina(劳累劳累(láolèi)(láolèi)性心绞痛性心绞痛))StableanginaStableangina((稳定性心绞痛稳定性心绞痛))Initialonsetangina(Initialonsetangina(初发型心绞痛初发型心绞痛))Acceleratedangina(Acceleratedangina(恶化性心绞痛恶化性心绞痛))Spontaneousangina(Spontaneousangina(自发性心绞痛自发性心绞痛))Anginadecubitus(Anginadecubitus(卧位型心绞痛卧位型心绞痛))VariantorvasospasticanginaVariantorvasospasticangina((变异性变异性[[痉挛性痉挛性]]心绞痛心绞痛))Acutecoronaryinsufficiency(Acutecoronaryinsufficiency(急性冠脉功能不全急性冠脉功能不全))Postinfarctionangina(Postinfarctionangina(梗死后心绞痛梗死后心绞痛))Mixedangina(Mixedangina(混合性心绞痛混合性心绞痛))UnstableanginaUnstableangina((不稳定性心绞痛不稳定性心绞痛))1.OVERVIEW1.OVERVIEW第六页，共三十一页。MyocardialMyocardialoxygendemandoxygendemandischieflydeterminedby:ischieflydeterminedby:•ContractilityContractility•HeartrateHeartrate•WalltensionWalltension•Preload(venousreturnPreload(venousreturn))•Afterload(arteriolarresistance)Afterload(arteriolarresistance)1.OVERVIEW1.OVERVIEWpreloadpreloadafterloadafterload第七页，共三十一页。MyocardialMyocardialby:by:•ReducingcontractilityReducingcontractility•ReducingheartrateReducingheartrate•ReducingthepreloadReducingthepreload•ReducingtheafterloadReducingtheafterload1.OVERVIEW1.OVERVIEWWalltensionWalltension第八页，共三十一...
