JournalofMinimallyInvasiveUrology,Dec.2022,Vol11,No6经尿道钬激光前列腺剜除术治疗高危高龄前列腺增生患者的安全性及近期疗效研究王健*于汝通张蕊孙国良蒋泉［摘要］目的：评估经尿道钬激光前列腺剜除术（HoLEP）治疗高危前列腺增生患者（BPH）的近期疗效及安全性。方法：收集70例高危高龄BPH患者随机分成HoLEP组（n=35）和TURP组（n=35）。对两组患者的围手术期情况、术后3个月的临床疗效以及术后并发症情况进行比较。结果：两组术后3个月的IPSS、RUV、QOL较术前降低，Qmax较术前升高，差异显著（P<0.05）。与TURP组比较，HoLEP组血红蛋白变化小[2.0（2.0，3.0）g/Lvs.4.0（2.0，9.0）g/L，P=0.000]，手术时间短[（66.14±16.24）minvs.（83.69±23.36）min,P<0.001]，留置尿管时间短[（2.49±0.62）dvs.（5.31±0.80）d,P=0.000]，切除腺体多[（44.09±15.83）gvs.（35.77±10.13）g,P=0.011],术后住院时间短[（4.68±1.04）dvs.（6.77±1.54）d,P<0.000]。HoLEP术后并发症例数低于TURP组（P<0.05）。结论：在治疗高危高龄BPH方面，两种手术方式近期疗效相当，但HoLEP恢复更快，更安全，是高危高龄BPH的更好的选择。［关键词］前列腺增生；前列腺切除除术［中图分类号］R699.8［文献标识码］A［DOI］10.19558/j.cnki.10-1020/r.2022.06.009EfficacyandsafetyofthetransurethralholmiumlaserenucleationofprostateintreatmentofelderlybenighprostatehyperplasiawithhighsurgicalriskWangJian*YuRutongZhangruiSunGuoliangJiangQuan（DepartmentofUrology，ChengdeCentralHospital，Chengde067000，China）Correspondingauthor：Wangjian，wangdi880120@163.comAbstractObjective：Toinvestigatetheprimaryeffectandsafetyoftransurethralholmiumlaserenucleationofprostate（HoLEP）intreatmentofhighsurgicalriskbenignprostatichyperplasia（BPH）.Methods：Atotalof70elder⁃lyandhighsurgicalriskBPHwererandomlyassignedintoHoLEPgroup（n=35）andtransurethralresectionoftheprostate（TURP）group（n=35）.TheclinicaldataofallthepatientswerecollectedandcomparedbetweentheHo⁃LEPandTURPgroup，includingthepre-operationcharacteristicandthreemonthafteroperationcharacteristicandcomplicationsafteroperation.Results：Comparedwiththedatabeforethesurgery，IPSSscore，RUV，andQOLscoreofthetwogroupsweregreatlydecreasedan...
