2023年4月第30卷第4期肺力咳胶囊联合盐酸氨溴索对慢性支气管炎患者血气分析指标及炎性因子的影响杨天坤（洛阳景华医院内二科，河南洛阳471003）【摘要】目的探讨肺力咳胶囊联合盐酸氨溴索治疗慢性支气管炎（CB）患者的效果。方法160例CB患者随机分为两组，对照组给予盐酸氨溴索治疗，观察组给予肺力咳胶囊联合盐酸氨溴索治疗，比较两组的临床疗效、炎性反应、血气分析指标、不良反应。结果治疗后，观察组的总有效率高于对照组，IL－6、TNF－α、CRP及PaCO2均低于对照组，PaO2高于对照组（P＜0．05）。两组的不良反应发生率比较，差异无统计学意义（P＞0．05）。结论肺力咳胶囊联合盐酸氨溴索治疗CB患者效果显著，可减轻炎性反应，改善血气分析指标，安全性高。【关键词】慢性支气管炎；肺力咳胶囊；盐酸氨溴索；血气分析指标；炎性因子中图分类号：R259文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.04.0507ImpactofFeilikeCapsuleCombinedwithAmbroxolHydrochlorideonBloodGasAnalysisIndicatorsandInflammatoryFactorsofPatientswithChronicBronchitis//YANGTiankun(2ndDepartmentofInternalMedicine,LuoyangJinghuaHospital,Luoyang471003,China)[Abstract]ObjectiveToexploretheeffectofFeilikecapsulecombinedwithambroxolhydrochlorideinthetreatmentofpatientswithchronicbronchitis(CB).Methods160CBpatientswererandomlydividedintotwogroups.Thecontrolgroupwastreatedwithambroxolhydrochloride,andtheobservationgroupwastreatedwithFeilikecapsulecombinedwithambroxolhydrochloride.Theclinicalefficacy,inflammatoryreaction,bloodgasanalysisindicatorsandadversereactionswerecomparedbetweenthetwogroups.ResultsAftertreatment,thetotaleffectiverateoftheobservationgroupwashigherthanthatofthecontrolgroup,IL-6,TNF-α,CRPandPaCO2werelowerthanthoseofthecontrolgroup,andPaO2washigherthanthatofthecontrolgroup(P<0.05).Nostatisticaldifferencewasfoundbetweenthetwogroupsintheincidenceofadversereactions(P>0.05).ConclusionsFeilikecapsulecombinedwithambroxolhydrochlorideinthetreatmentofCBpatientshassignificanteffectandhighsafety,whichcanrelieveinflammatoryreaction,andimprovethebloodgasanalysisindicators.[Keywords]Chronicbronchitis;Feilikecapsules;Ambroxolhydrochloride;Bloodgasanalysisin...
