2023年4月第30卷第4期腹腔镜下修补术联合奥美拉唑三联治疗胃、十二指肠溃疡穿孔的效果观察李正伟，张莹楠，刘奎（河南科技大学第一附属医院外科，河南洛阳471000）【摘要】目的探讨腹腔镜下修补术联合奥美拉唑三联治疗胃、十二指肠溃疡穿孔的效果。方法86例胃、十二指肠溃疡穿孔患者随机分为两组，对照组实施腹腔镜下修补术治疗，观察组实施腹腔镜下修补术联合奥美拉唑三联治疗，比较两组的临床疗效、临床指标、术后并发症及穿孔复发率。结果治疗后，观察组的总有效率高于对照组，拔管时间、住院时间均短于对照组，术后并发症发生率低于对照组（P＜0．05）。两组术后3个月内的穿孔复发率比较，差异无统计学意义（P＞0．05）。结论腹腔镜下修补术联合奥美拉唑三联治疗胃、十二指肠溃疡穿孔的效果确切，可降低术后并发症发生风险。【关键词】腹腔镜下修补术；奥美拉唑三联；胃、十二指肠溃疡穿孔；并发症中图分类号：R573.1文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.04.0465ObservationontheEffectofLaparoscopicRepairCombinedwithOmeprazoleTripleTherapyintheTreatmentofGastric-DuodenalUlcerPerforation//LIZhengwei,ZHANGYingnan,LIUKui(DepartmentofSurgery,theFirstAffiliatedHospitalofHe'nanUniversityofScienceandTechnology,Luoyang471000,China)[Abstract]ObjectiveToexploretheeffectoflaparoscopicrepaircombinedwithomeprazoletripletherapyinthetreatmentofgastric-duodenalulcerperforation.Methods86patientswithgastric-duodenalulcerperforationwererandomlydividedintotwogroups.Thecontrolgroupwastreatedwithlaparoscopicrepair,andtheobservationgroupwastreatedwithlaparoscopicrepaircombinedwithomeprazoletripletherapy.Theclinicalefficacy,clinicalindicators,postoperativecomplicationsandperforationrecurrenceratewerecomparedbetweenthetwogroups.ResultsAftertreatment,thetotaleffectiverateoftheobservationgroupwashigherthanthatofthecontrolgroup,theextubationtimeandhospitalizationtimewereshorterthanthoseofthecontrolgroup,andtheincidenceofpostoperativecomplicationswaslowerthanthatofthecontrolgroup(P<0.05).Nosignificantdifferencewasfoundintheperforationrecurrenceratewithin3monthsaftersurgerybetweenthetwogroups(P>0.05).ConclusionsLaparoscopicrepaircombinedwithomeprazol...
