2023年5月第30卷第5期M22优化强脉冲光治疗睑板腺功能障碍相关性干眼患者的效果观察秦晓艳，皮百木（开封市中心医院眼科，河南开封475000）【摘要】目的观察M22优化强脉冲光治疗睑板腺功能障碍（MGD）相关性干眼患者的临床效果。方法将82例MGD相关性干眼患者随机分为两组各41例。对照组采用睑板腺按摩及0．3％玻璃酸钠滴眼液局部点眼治疗，观察组在对照组基础上采用M22强脉冲光治疗，比较两组的主观症状、泪膜破裂时间（BUT）、泪河高度（TMH）及睑板腺分泌情况。结果治疗后，观察组眼表疾病指数（OSDI）评分、睑板腺分泌评分低于对照组，泪膜BUT长于对照组，TMH高于对照组（P＜0．05）。结论M22优化强脉冲光治疗MGD相关性干眼，可明显增加患者泪膜BUT、TMH，改善睑板腺分泌，缓解患者主观症状。【关键词】睑板腺功能障碍；干眼；M22优化强脉冲光中图分类号：R777.34文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.05.0603ObservationontheEffectofM22OptimizedIntensePulsedLightintheTreatmentofPatientswithDryEyeAssociatedwithMeibomianGlandDysfunctionQINXiaoyan,PIBaimu(DepartmentofOphthalmology,KaifengCentralHospital,Kaifeng475000,China)[Abstract]ObjectiveToobservetheclinicaleffectofM22optimizedintensepulsedlightinthetreatmentofpatientswithdryeyeassociatedwithmeibomianglanddysfunction(MGD).Methods82patientswithdryeyeassociatedwithMGDwererandomlydividedintotwogroups,with41casesineachgroup.Thecontrolgroupwastreatedwithmeibomianglandmassageand0.3%sodiumhyaluronateeyedrops,andtheobservationgroupwastreatedwithM22optimizedintensepulsedlightonthebasisofthecontrolgroup.Thesubjectivesymptoms,tearfilmbreak-uptime(BUT),tearmeniscusheight(TMH)andmeibomianglandsecretionwerecomparedbetweenthetwogroups.ResultsAftertreatment,theocularsurfacediseaseindex(OSDI)scoreandmeibomianglandsecretionscoreoftheobservationgroupwerelowerthanthoseofthecontrolgroup,thetearfilmBUTwaslongerthanthatofthecontrolgroup,andtheTMHwashigherthanthatofthecontrolgroup(P<0.05).ConclusionsM22optimizedintensepulsedlightinthetreatmentofpatientswithdryeyeassociatedwithMGDcansignificantlyincreasethetearfilmBUTandTMH,improvethemeibomianglandsecretionandalleviatethesubjectivesymptoms.[...
