PHOTO(TOP):GENEVIEVEMARTIN/ORNL1JULY2016•VOL353ISSUE62943SCIENCEsciencemag.org1JULY2016•VOLUME353•ISSUE6294CONTENTS29THEEVOLUTIONARYPATHOFLEASTRESISTANCEEvolutionfavoredteethwiththickerenameloversharplycrestedteethinhomininsconfrontedwithtoughdietsByP.S.UngarandL.J.Hlusko30PROMOTINGCNSREPAIRWhatinfluencesglialandneuronalresponsetoneurodegeneration?ByE.G.CameronandJ.L.Goldberg▶RESEARCHARTICLEP.4332HOWCLIMATECHANGEAFFECTSPLANTS’SEXLIVESShiftsinplantsexratioshelpplantspeciestoexpandupslopeinawarmerclimateByJ.R.EttersonandS.J.Mazer▶REPORTP.6933YobMAKESMOSQUITOESMALEAgender-switchgeneopensavenuestomalariacontrolByS.P.Sinkins▶REPORTP.67POLICYFORUM35REFORMSTOIMPROVEU.S.GOVERNMENTACCOUNTABILITYBillwillencodea“presumptionofopenness”intolawByA.B.HowardandP.McDermott17SCIENTISTSCHEERSENATEBILLLong-awaitedsuccessortoCOMPETESActrejectscontroversialHouseapproachtomanagingfederalresearchByJ.MervisFEATURE18SOUTHAFRICA’SBIDTOENDAIDSThetoolsexist,butthecountry’sepidemic—thelargestintheworld—won’tyieldeasilyByJ.Cohen▶PODCAST153532&69PlantreproductioninachangingclimateScienceStaf..................................................6NewProducts...............................................87ScienceCareers...........................................88INSIGHTSLETTERS22NEXTGENVOICESPERSPECTIVES26HOWFRIGATEBIRDSSOARAROUNDTHEDOLDRUMSFrigatebirdsforageovervastdistancesbygettingboostsfromthermalsandtradewindsByR.B.HueyandC.Deutsch▶REPORTP.7428TIMINGPHOTOEMISSION—FINALSTATEMATTERSUltrafastspectroscopycantracktheelectrondynamicsofthephotoemissionprocessByU.BovensiepenandM.Ligges▶REPORTP.62Neutrondetectorsthateasedemandforascarceisotope.NEWSINBRIEF8NewsataglanceINDEPTH12‘BREXIT’CASTSPALLONFUTUREOFU.K.SCIENCEFunding,freedomofmovement,andavoiceinEurope’ssciencepolicyareallinquestionByD.Clery▶EDITORIALP.714FIGHTINGAUTOIMMUNITYWITHIMMUNECELLSEngineeredTcellscanselectivelydestroysourcesofenemyantibodiesByM.Leslie▶REPORTBYC.T.ELLEBRECHTETAL.10.1126/science.aaf675615RESEARCHERSRIS...