235专题论述《食品工业》2023年第44卷第2期金针菇多糖的提取纯化及生物活性研究进展申鑫玉，黄悦同，阿依江·特列吾汗，郑艳，岳喜庆*沈阳农业大学食品学院（沈阳110866）摘要金针菇(Flammulinavelutipes)是一种常见的食用菌,在我国资源较为丰富,其在食品和药品等领域都有很大的应用价值。金针菇多糖(Flammulinavelutipespolysaccharide,FVP)作为金针菇的主要活性成分之一,具有抗氧化、抗肿瘤、免疫调节、改善学习记忆、抗炎及保肝等生物活性作用,被应用于膳食补充剂和功能性食品中。基于近年来国内外对金针菇多糖的研究现状,总结并对比金针菇多糖的提取和分离纯化方法,归纳金针菇多糖的结构及生物活性的研究进展,并对金针菇多糖可能的研究方向进行展望,旨在为深入研究金针菇多糖的构效关系及进一步开发与应用提供理论依据。关键词金针菇多糖;提取;分离纯化;结构;生物活性ResearchProgressonExtraction,PurificationMethodsandBioactivitiesofFlammulinavelutipesPolysaccharidesSHENXinyu,HUANGYuetong,AYIJIANGTeliewuhan,ZHENGYan,YUEXiqing*CollegeofFoodScience,ShenyangAgriculturalUniversity(Shenyang110866)AbstractFlammulinavelutipesisacommonediblefungus,whichisarelativelyabundantresourceinChina.Ithasagreatapplicationvalueinfoodandmedicinefields.AsoneofthemostimportantbiologicallyactivesubstancesinFlammulinavelutipesbarriers,Flammulinavelutipespolysaccharide(FVP)hasbeenprovedthatithasantioxidant,antitumor,immunomodulatory,learningandmemoryimprovement,anti-inflammatoryandotherbioactiveeffects.TheFVPhasbeenusedindietarysupplementsandfunctionalfoods.Standonrecentdomesticandinternationalstudies,summarizeandcomparetheextractionandpurificationmethodsofFVP.Furthermore,thecurrentresearchstreaminthisfieldissummarized,andthedirectionforthefutureresearchintheFVPfieldisproposed.Thetheoreticalbasisforthefutureresearchonthestructure-activityrelationshipsinFVPisputforward,toprovidetheimplicationsforthefurtherdevelopmentandapplicationofthestructure-activityrelationshipsinFVP.KeywordsFlammulinavelutipespolysaccharide;extraction;separationandpurification;structure;biologicalactivity*通信作者；基金项目：辽宁省“兴辽英才计划”科技创新领军人才项目（XLYC190208...
