介入放射学杂志2023年2月第32卷第2期JInterventRadiol2023,Vol.32,No.2·综述Generalreview·C臂锥形束CT灌注在急性缺血性脑卒中诊治中的应用进展方慧，徐浩洋，朱悦琦，程英升【摘要】急性缺血性脑卒中（AIS）具有高致死致残率。脑组织缺血时间越长临床预后越差，尽早恢复缺血区血流灌注，挽救缺血半暗带一直是AIS诊治重点，而启动再灌注治疗前快速识别半定量缺血半暗带是影像学筛查核心内容。基于DSA设备的新兴断层成像C臂锥形束CT（CBCT）与传统CT相比更有利于实现AIS一站式诊治，明显缩短缺血组织再灌注时间，获得良好临床预后。然而由于现有设备硬件和算法限制，该技术目前尚未广泛应用于临床。本文就CBCT灌注技术在AIS相关成像方法、原理及其在临床诊治中应用进展作一综述。【关键词】急性缺血性脑卒中；C臂锥形束CT；脑灌注成像；临床应用中图分类号：R743.3文献标志码：A文章编号:1008-794X（2023）-02-0192-04AdvancesintheapplicationofC-armconebeamCTperfusionforacuteischemicstrokeFANGHui,XUHaoyang,ZHUYueqi,CHENGYingsheng.DepartmentofInterventionalRadiology,AffiliatedSixthPeople’sHospital,SchoolofMedicine,ShanghaiJiaoTongUniversity,Shanghai200233,ChinaCorrespondingauthor:ZHUYueqi,E-mail:zhuyueqi@hotmail.com【Abstract】Acuteischemicstroke（AIS）carrieshighdisabilityandmortalityrate.Thelongerischemictimethebraintissuessuffers,theworseclinicalprognosisthepatientswouldhave.Therefore,earlyrecoveryofbloodperfusioninischemicareasandrescueofischemicpenumbrahavealwaysbeenthefocusofdiagnosisandtreatmentofAIS,andrapididentificationofsemi-quantitativeischemicpenumbrabeforeinitiatingreperfusiontreatmentisthecorecontentofimagingscreening.TheemergingC-armcone-beamCT（CBCT）,whichisdevelopedbasedonDSAdevice,issuperiortotraditionalCTinachievingone-stop-shopdiagnosisandtreatmentofAIS.C-armCBCTperfusioncansignificantlyshortenthereperfusiontimeforischemictissuesandobtaingoodclinicalprognosis.However,inclinicalpracticethistechniquehasnotbeenwidelyemployedyetduetothehardwareandalgorithmlimitationsofexistingavailabledevices.ThispaperreviewstheapplicationprogressofC-armCBCTperfusiontechnologyinAIS,focusingonitsimagingmethod,imagingprincipleandit...
