中国实用口腔科杂志2023年3月第16卷第2期[18]TurnerJA,ManclL,HugginsKH,etal.Targetingtemporoman⁃dibulardisorderpaintreatmenttohormonalfluctuations:aran⁃domizedclinicaltrial[J].Pain,2011,152(9):2074-2084.[19]马绪臣,张震康.颞下颌关节紊乱病双轴诊断的临床意义和规范治疗的必要性[J].中华口腔医学杂志,2005,40(5):6-8.[20]SójkaA,StelcerB,RoyM,etal.IstherearelationshipbetweenpsychologicalfactorsandTMD?[J].BrainBehav,2019,9(9):e01360.[21]WuY,XiongX,FangX,etal.PsychologicalstatusofTMDpa⁃tients,orthodonticpatientsandthegeneralpopulationduringtheCOVID-19pandemic[J].PsycholHealthMed,2021,26(1):62-74.[22]NamvarMA,AfkariBF,MoslemkhaniC,etal.Therelationshipbetweendepressionandanxietywithtemporomandibulardisor⁃dersymptomsindentalstudents[J].Maedica(Bucur),2021,16(4):590-594.[23]Iranzo-CortésJE,Montiel-CompanyJM,Bellot-ArcisC,etal.Factorsrelatedtothepsychologicalimpactofmalocclusioninadolescents[J].SciRep,2020,10(1):13471.[24]IbiM.Inflammationandtemporomandibularjointderange⁃ment[J].BiolPharmBull,2019,42(4):538-542.[25]NakashimaM,SakaiT,HiraiwaH,etal.RoleofS100A12inthepathogenesisofosteoarthritis[J].BiochemBiophysResCommun,2012,422(3):508-514.[26]HoltDW,HendersonML,StockdaleCE,etal.Osteoarthritis-likechangesintheheterozygoussedcmouseassociatedwiththeHtrA1-Ddr2-Mmp-13degradativepathway:anewmodelofosteoarthritis[J].OsteoarthritisCartilage,2012,20(5):430-439.[27]LarkinDJ,KartchnerJZ,DoxeyAS,etal.Inflammatorymark⁃ersassociatedwithosteoarthritisafterdestabilizationsurgeryinyoungmicewithandwithoutReceptorforAdvancedGlycationEnd-products(RAGE)[J].FrontPhysiol,2013,4:121.[28]王美青.颞下颌关节紊乱病咬合病因研究进展[J].中国实用口腔科杂志,2009,2(3):131-134.[29]RenH,YangH,XieM,etal.Chondrocyteapoptosisinratman⁃dibularcondylesinducedbydentalocclusionduetomitochon⁃drialdamagecausedbynitricoxide[J].ArchOralBiol,2019,101:108-121.[30]YangH,WenY,ZhangM,e...