文章编号:1000-5641(2023)02-0161-077种不同成分消毒剂对MS2噬菌体杀灭效果的比较李宇1,葛振鸣2,3(1.3M中国有限公司中国研发中心,上海200233;2.华东师范大学河口海岸学国家重点实验室,上海200241;3.崇明生态研究院,上海202162)摘要:以MS2噬菌体为指示微生物,检验了7种不同成分的消毒剂(双氧水、乙醇、发酵乳酸消毒剂、络合碘消毒剂、复合季铵盐消毒剂、含氯消毒剂和过氧乙酸消毒剂)对噬菌体的杀灭效果.结果表明,被广泛使用的消毒剂对病毒杀灭的效果差异较大.络合碘消毒剂具有最强的杀灭作用,其次为复合季铵盐消毒剂和过氧乙酸消毒剂,而双氧水、乙醇和发酵乳酸消毒剂的杀灭效果较差.该试验结果可为合理配置消杀环境中有害微生物的消毒剂提供参考依据.关键词:消毒剂;MS2噬菌体;杀灭率;灭活对数值中图分类号:R187+.2文献标志码:ADOI:10.3969/j.issn.1000-5641.2023.02.017DisinfectioneffectofsevenfrequentlyuseddisinfectantsonbacteriophageMS2LIYu1,GEZhenming2,3(1.3MChinaR&DCenter,3MChinaCo.Ltd.,Shanghai200233,China;2.StateKeyLaboratoryofEstuarineandCoastalResearch,EastChinaNormalUniversity,Shanghai200241,China;3.InstituteofEco-Chongming,Shanghai202162,China)Abstract:Inthisstudy,theMS2phageswereusedasanindicatormicroorganismtotestthefunctionofsevendisinfectantswithdifferentcomponents:hydrogenperoxide,ethanol,fermentedlacticaciddisinfectant,iodinedisinfectant,quaternaryammoniumdisinfectant,chlorine-containingdisinfectant,andperaceticaciddisinfectant.Ourresultsshowedthatthevirusdisinfectionratevariednotablybetweentheselecteddisinfectants.Theiodinedisinfectantexhibitedthestrongestdisinfectioneffect,followedbythequaternaryammoniumsaltdisinfectantandtheperaceticaciddisinfectant,whilethedisinfectioneffectsofhydrogenperoxide,ethanol,andfermentationlacticaciddisinfectantwereinadequate.Thetestresultsprovideareferencefortheefficientutilizationofvariousdisinfectantstoeliminateharmfulmicroorganismsintheenvironment.Keywords:disinfectant;MS2phage;disinfectionrates;disinfectionlogarithmvalues0引言随着新型冠状病毒感染(coronavirusdisease2019,COVID-19)疫情在全球蔓延,世界卫生组织不收稿日期:2021-12-10基金项目:国家自然科学基金(41871088);华东师范大...