Designation:E2402−11StandardTestMethodforMassLossandResidueMeasurementValidationofThermogravimetricAnalyzers1ThisstandardisissuedunderthefixeddesignationE2402;thenumberimmediatelyfollowingthedesignationindicatestheyearoforiginaladoptionor,inthecaseofrevision,theyearoflastrevision.Anumberinparenthesesindicatestheyearoflastreapproval.Asuperscriptepsilon(´)indicatesaneditorialchangesincethelastrevisionorreapproval.1.Scope1.1Thismethodprovidesproceduresforvalidatingmasslossandresiduemeasurementsbythermogravimetricanalyzers(TGA)andanalyticalmethodsbaseduponthemeasurementofmasslossorresiduecontent.Performanceparametersdeter-minedincludemasslossandresiduerepeatability(precision),detectionlimit,quantitationlimit,linearityandbias.1.2Validationofapparatusperformanceandanalyticalmethodsisrequestedorrequiredforqualityinitiativesorwhereresultsmaybeusedforlegalpurposes.1.3ThevaluesstatedinSIunitsaretoberegardedasstandard.Nootherunitsofmeasurementareincludedinthisstandard.1.4ThereisnoISOstandardequivalenttothismethod.1.5Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappro-priatesafetyandhealthpracticesanddeterminetheapplica-bilityofregulatorylimitationspriortouse.2.ReferencedDocuments2.1ASTMStandards:2E177PracticeforUseoftheTermsPrecisionandBiasinASTMTestMethodsE473TerminologyRelatingtoThermalAnalysisandRhe-ologyE1142TerminologyRelatingtoThermophysicalPropertiesE1582PracticeforCalibrationofTemperatureScaleforThermogravimetryE1970PracticeforStatisticalTreatmentofThermoanalyticalDataE2040TestMethodforMassScaleCalibrationofThermo-gravimetricAnalyzersE2161TerminologyRelatingtoPerformanceValidationinThermalAnalysis2.2OtherStandard:UnitedStatesFoodandDrugAdministration,Q2BValida-tionofAnalyticalProcedures:Methodology,62FR27464,May19,199733.Terminology3.1TechnicaltermsusedinthisstandardaredefinedinPracticeE177andinTerminologiesE473,E1142,andE2161.3.2DefinitionsofTermsSpecifictoThisStandard:3...
