慢性阻塞性肺病的新进展2014--cai.pptVIP免费

慢性阻塞性肺病的新进展慢性阻塞性肺病的新进展清华大学第一附属医院呼吸科清华大学第一附属医院呼吸科•GOLD颁布的COPD全球策略2014年最新更新慢性阻塞性肺疾病急性加重(AECOPD)诊治中国专家共识(草案)GlobalStrategyforDiagnosis,ManagementandPreventionofCOPD,2013:ChaptersGlobalStrategyforDiagnosis,ManagementandPreventionofCOPD,2013:ChaptersDefinitionandOverviewDiagnosisandAssessmentTherapeuticOptionsManageStableCOPDManageExacerbationsManageComorbiditiesDefinitionandOverviewDiagnosisandAssessmentTherapeuticOptionsManageStableCOPDManageExacerbationsManageComorbiditiesUpdated2013©2013GlobalInitiativeforChronicObstructiveLungDiseaseCOPDCOPD的定义的定义•COPD是一种可以预防和可以治疗的常见疾病,其特征是持续存在的气流受限。气流受限呈进行性发展,伴有气道和肺对有害颗粒或气体所致慢性炎症反应的增加。•急性加重和合并症影响患者整体疾病的严重程度。COPD气流受限的发病机制SmallAirwaysDisease•Airwayinflammation•Airwayfibrosis,luminalplugs•IncreasedairwayresistanceParenchymalDestruction•Lossofalveolarattachments•DecreaseofelasticrecoilAIRFLOWLIMITATION©2013GlobalInitiativeforChronicObstructiveLungDiseaseCOPD的危险因素肺的生长发育性别年龄呼吸道感染社会经济条件哮喘气道高反应性慢性支气管炎基因有害颗粒暴露吸烟职业粉尘，有机物，无机物室内燃料燃烧和通风不良室外空气污染©2013GlobalInitiativeforChronicObstructiveLungDiseaseCOPD的危险因素GenesGenesInfectionsInfectionsSocio-economicSocio-economicstatusstatusAgingPopulationsAgingPopulations©2013GlobalInitiativeforChronicObstructiveLungDiseaseGlobalStrategyforDiagnosis,ManagementandPreventionofCOPD,2013:ChaptersGlobalStrategyforDiagnosis,ManagementandPreventionofCOPD,2013:ChaptersDefinitionandOverviewDiagnosisandAssessmentTherapeuticOptionsManageStableCOPDManageExacerbationsManageComorbiditiesDefinitionandOverviewDiagnosisandAssessmentTherapeuticOptionsManageStableCOPDManageExacerbationsManageComorbiditiesUPDATED2013©2013GlobalInitiativeforChronicObstructiveLungDiseaseSYMPTOMSchroniccoughchroniccoughsho...