第39卷第2期2023年2月长春中医药大学学报JournalofChangchunUniversityofChineseMedicineVol.39No.2Feb.2023—119—DOI:10.13463/j.cnki.cczyy.2023.02.001重构本草——半夏段丽云1,赵金悦2,周丹妮3,张亚杰1*(1.中国中医科学院广安门医院代谢病研究所,北京100053;2.长春中医药大学,长春130117;3.甘肃中医药大学,兰州730000)摘要:通过古籍文献调研、中药现代研究进展及其研究成果的梳理,结合中医临床及中药学等学科领域内的专家学者的认识及应用经验,经讨论认为半夏:功效主要为燥湿化痰,降逆止呕,消痞散结;其症靶为恶心呕吐、失眠;现代药理研究发现,半夏及其有效成分具有止吐、保护胃黏膜、止咳平喘、调血脂、镇静、抗肿瘤等作用;半夏有毒,生品内服宜慎,内服一般炮制后使用,不宜与川乌、制川乌、草乌、制草乌、附子同用;经方及历代经典方剂之中半夏用量为0.19~268g,现代医家半夏用量为6~60g,内服时当根据不同疾病,不同证型、症状辨证使用。关键词:半夏;症靶;恶心呕吐;失眠;临床回归中图分类号:R282文献标志码:A文章编号:2095-6258(2023)02-0119-04ReconstructionofChinesemateriamedica-pinelliatuberDUANLiyun1,ZHAOJinyue2,ZHOUDanni3,ZHANGYajie1*(1.InstituteofMetabolicDiseases,Guang'anmenHospital,ChinaAcademyofChineseMedicalSciences,Beijing100053,China;2.ChangchunUniversityofChineseMedicine,Changchun130117,China;3.GansuUniversityofChineseMedicine,Lanzhou730000,China)Abstract:Basedontheinvestigationofancientbooksandliterature,theprogressandachievementsofmodernresearchontraditionalChinesemedicine,andtheunderstandingandapplicationexperienceofexpertsandscholarsinthefieldofclinicalChinesemedicineandChinesemateriamedica,itisconsideredthatpinelliatuberhasthefollowingcharacteristics:Itsmaineffectsareeliminatingdampnessandresolvingphlegm,loweringadverseqiandstoppingvomiting,andrelievingoppressionandresolvinghardmasses.Itssymptomtargetsarenausea,vomitingandinsomnia.Modernpharmacologyhasfoundthatpinelliatuberanditseffectivecomponentshavethefunctionsofstoppingvomiting,protectinggastricmucosa,relievingcoughandasthma,regulatingbloodlipid,tranquilizingandresistingtumor.Thisproductistoxic,sorawpinelliatubershouldbetakenwithcaut...