CHINAMEDICINEANDPHARMACYVol.13No.2January20231782023年1月第13卷第2期·病例报告·重症急性胰腺炎合并多器官功能障碍1例王雪婷王志平江苏省南通市第四人民医院重症医学科，江苏南通226000[摘要]重症急性胰腺炎（SAP）是伴有全身及局部并发症的急性胰腺炎，属急性胰腺炎的特殊类型，是一种病情险恶、并发症多、病死率高的急腹症，占整个急性胰腺炎的10%～20%。我科近期收治一名急性胰腺炎患者，观察其发病过程、病情进展、整体诊疗、生化指标等，认定为SAP合并多器官功能障碍，然而该患者的临床首发症状却非SAP的典型表现，迷惑性较大，易干扰临床诊疗工作，因此本文通过介绍该病例发病、诊疗过程，病情变化及相关生化指标改变，对SAP的发病机制、临床表现、治疗及预后进行总结，以期对该病的临床诊疗提供帮助。[关键词]重症急性胰腺炎；多器官功能障碍；急性呼吸窘迫综合征；连续肾脏替代疗法[中图分类号]R576[文献标识码]A[文章编号]2095-0616（2023）02-0178-05AcaseofsevereacutepancreatitiswithmultipleorgandysfunctionsyndromeWANGXuetingWANGZhipingDepartmentofCriticalCareMedicine,NantongFourthPeople’sHospital,Jiangsu,Nantong226000,China[Abstract]Severeacutepancreatitis(SAP)isanacutepancreatitis(AP)withsystemicandlocalcomplications,belongingtothespecialtypeofAPs.Itisanacuteabdominaldiseasewithdangerouscondition,manycomplicationsandhighmortality,accountingfor10%-20%ofthetotalnumberofAPs.ApatientwithAPisadmittedtoourdepartmentrecently.Throughoutthepathogenesis,diseaseprogression,overalldiagnosisandtreatmentandbiochemicalindexes,weidentifyitasSAPwithmultipleorgandysfunctionsyndrome(MODS).However,thepatient’sinitialclinicalsymptomsarenotthetypicalmanifestationsofSAP,whichisconfusingandeasytointerferewithclinicaldiagnosisandtreatment.Therefore,byintroducingthepathogenesis,diagnosisandtreatmentprocess,changesoftheconditionandrelevantbiochemicalindexes,thisarticlesummarizesthepathogenesis,clinicalmanifestations,treatmentandrecoveryofsevereacutepancreatitis,soastoofferhelpfortheclinicaldiagnosisandtreatmentofthisdisease.[Keywords]Severeacutepancreatitis;Multipleorgandysfunctionsyndrome;Acuterespiratorydistresssyndrome;Continuousrenalrepl...
