肿瘤防治研究2023年第50卷第1期CancerResPrevTreat,2023,Vol.50,No.1·81·doi:10.3971/j.issn.1000-8578.2023.22.0677肝外胆管癌术后辅助放化疗的现况分析杨潇，彭慧，庄亮CurrentSituationofPostoperativeAdjuvantChemoradiotherapyforExtrahepaticCholangiocarcinomaYANGXiao,PENGHui,ZHUANGLiangDepartmentofOncology,TongjiHospital,TongjiMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan430000,ChinaCorrespondingAuthor:ZHUANGLiang,E-mail:mrzhuangliang@126.comAbstract:Inrecentyears,theincidenceofextrahepaticcholangiocarcinoma(ECC)hasbeenincreasingannually.Asaresultoffrequentlyinvadingadjacentstructures,suchashepaticartery,hepaticvein,andportalvein,andlowradicalresectionrate,theprognosisispoor.Evenifradicalresectioniscompletedearly,the5-yearsurvivalrateisstilllessthan30%.Atpresent,whetherpostoperativeadjuvanttherapycanimprovetheprognosisofECCremainsaresearchhotspotandacontroversialpoint.ThisarticlewillcombinethelatestresearchresultstodiscusstheplanandstatusofpostoperativeadjuvanttherapyafterECC,aswellasanalyzetheeffectofpostoperativeadjuvanttherapyonECC.Keywords:Extrahepaticcholangiocarcinoma;Adjuvantchemotherapy;Adjuvantradiotherapy;AdjuvantchemoradiotherapyFunding:BeijingXisikeClinicalOncologyResearchFoundation(No.Y-SY201901-0074);NaturalScienceFoundationofHubeiProvince(No.2021CFB331);HubeiChenXiaopingScienceandTechnologyDevelopmentFoundationHepatobiliaryandPancreaticCancerFund(No.CXPJJH12000001-2020344)Competinginterests:Theauthorsdeclarethattheyhavenocompetinginterests.摘要：近年来，肝外胆管癌的发病率逐年递增。因其易侵犯周围肝动脉、肝静脉、门静脉，且根治性切除率低，预后较差，即使早期完成根治术，5年生存率仍不足30%。术后辅助治疗能否改善肝外胆管癌的预后一直是研究的热点及争议点，本文将结合最新的研究进展，讨论肝外胆管癌术后辅助治疗的方案，分析术后辅助治疗对于肝外胆管癌预后的意义。关键词：肝外胆管癌；辅助化疗；辅助放疗；辅助放化疗中图分类号：R735.7开放科学(资源服务)标识码(OSID)：收稿日期：2022-06-20；修回日期：2022-08-10基金项目：希思科-石药肿瘤研究基金项目（Y-SY201901-0074）...
