海南医学2023年2月第34卷第4期HainanMedJ,Feb.2023.Vol.34,No.4278(52):52412-52424.[36]LiwoszA,LeiT,KukuruzinskaMA.N-glycosylationaffectsthemo-lecularorganizationandstabilityofE-cadherinjunctions[J].JBiolChem,2006,281(32):23138-23149.[37]MenniC,GudeljI,Macdonald-DunlopE,etal.GlycosylationprofileofimmunoglobulinGiscross-sectionallyassociatedwithcardiovas-culardiseaseriskscoreandsubclinicalatherosclerosisintwoinde-pendentcohorts[J].CircRes,2018,122(11):1555-1564.[38]RodriguesJG,BalmanaM,MacedoJA,etal.Glycosylationincan-cer:Selectedrolesintumourprogression,immunemodulationandmetastasis[J].CellImmunol,2018,333:46-57.[39]LinMC,HuangMJ,LiuCH,etal.GALNT2enhancesmigrationandinvasionoforalsquamouscellcarcinomabyregulatingEGFRglyco-sylationandactivity[J].OralOncol,2014,50(5):478-484.[40]ChenL,LiY,ZengS,etal.TheinteractionofO-GlcNAc-modifiedNLRX1andIKK-alphamodulatesIL-1betaexpressioninM1macro-phages[J].InVitroCellDevBiolAnim,2022,58(5):408-418.[41]XuY,ShengX,ZhaoT,etal.O-GlcNAcylationofMEK2promotestheproliferationandmigrationofbreastcancercells[J].Glycobiolo-gy,2021,31(5):571-581.[42]ColombF,Krzewinski-RecchiMA,ElMF,etal.TNFregulatessi-alyl-Lewisxand6-sulfo-sialyl-Lewisxexpressioninhumanlungthroughup-regulationofST3GAL4transcriptisoformBX[J].Bio-chimie,2012,94(9):2045-2053.[43]PetrusP,LecoutreS,DolletL,etal.Glutaminelinksobesitytoin-flammationinhumanwhiteadiposetissue[J].CellMetab,2020,31(2):375-390.[44]FabianO,KamaradovaK.Morphologyofinflammatoryboweldis-eases(IBD)[J].CeskPatol,2022,58(1):27-37.[45]VerhelstX,DiasAM,ColombelJF,etal.Proteinglycosylationasadiagnosticandprognosticmarkerofchronicinflammatorygastroin-testinalandliverdiseases[J].Gastroenterology,2020,158(1):95-110.[46]MakinoA,DaiA,HanY,etal.O-GlcNAcaseoverexpressionrevers-escoronaryendothelialcelldysfunctionintype1diabeticmice[J].AmJPhysiolCellPhysiol,2015,309(9):C593-C599.[47]YaoD,XuL,XuO,etal.O-linkedbeta-N-acetylglucosaminemodifi-cationofA20enhancestheinhibitionofNF-kappaB(NuclearFac-tor-kappaB)activationandelici...
