［作者单位］1.电子科技大学医学院附属绵阳医院·绵阳市中心医院皮肤科，四川绵阳621000;2.电子科技大学医学院附属绵阳医院·绵阳市中心医院病理科，四川绵阳621000［通信作者］黄忠奎，E-mail:HuangzK71@sina.com［网络首发时间］2022-09-0516∶19［网络首发地址］https://kns.cnki.net/kcms/detail/61.1197.Ｒ.20220905.0942.001.html2023年3月第37卷第3期Mar.2023，Vol．37，No．3347http://pfxbxzz.paperopen.com泛发型环状肉芽肿1例易清玲1，柯琦2，黄忠奎1，何沅莉1［摘要］患者男，73岁，弥漫性红色丘疹、斑块10个月。躯干、上肢弥漫性鲜红色丘疹，大部分丘疹融合成斑块，边缘隆起，排列成环状，部分融合成网状。皮损组织病理示:表皮轻度角化过度，真皮浅层见栅栏状肉芽肿形成，并见多核巨细胞形成，血管及附属器周围见散在淋巴细胞浸润;阿新蓝染色阴性。诊断:环状肉芽肿。给予口服阿维A胶囊、维生素E软胶囊，外用卤米松乳膏等治疗后明显好转。［关键词］环状肉芽肿;泛发型;组织病理;阿新蓝染色［中图分类号］Ｒ758.6［文献标志码］B［文章编号］1001－7089(2023)03－0347－04［DOI］10．13735/j．cjdv．1001-7089．202202092GeneralizedGranulomaAnnulare:ACaseＲeportYIQingling1，KEQi2，HUANGZhongkui1，HEYuanli1(1.DepartmentofDermatology，MianyangCentralHospital，SchoolofMedicine，UniversityofElectronicScienceandTechnologyofChina，Mianyang621000，China;2.DepartmentofPathology，MianyangCentralHospital，SchoolofMedicine，UniversityofElectronicScienceandTechnologyofChina，Mianyang621000，China)［Correspondingauthor］HUANGZhongkui，E-mail:HuangzK71@sina.com［Abstract］A73-year-oldmalepatientpresentedwitha10-monthhistoryofdiffuseredpapulesandplaquesalloverthebody.Therewerediffusebrightredpapulesonthetrunkandupperlimbs.Mostofthepapuleswerefusedintopatcheswithraisededges，arrangedinringandpartlyfusedintomesh.Histopathologyoftheskinlesionsshowedmildhyperkeratosisoftheepidermis，theformationofpalisadegranulomasandmultinucleatedgiantcellinthesuperficialdermis，andthescatteredlymphocyteinfiltrationaroundbloodvesselsandappendages.Acianbluestainingwasnegative.Thediagnosisofgranulomaannularewasmade.Aftertreatmentwithoralacitretincapsules，vitaminEsoftcapsule...
