收稿日期:２０２３Ｇ０４Ｇ０９作者简介:刘婷(１９９４—),女,硕士,主治医师,主要从事浅表脏器及超声心动图的研究.经皮超声造影对乳腺癌患者腋窝前哨淋巴结的应用价值刘婷,郑巍,余美琴,王婧玲,聂小艳,熊海蔚,许志辉,张丽丽(南昌大学第一附属医院超声医学科,南昌３３０００６)摘要:目的探讨经皮超声造影(CEUS)对乳腺癌腋窝前哨淋巴结转移的诊断及定位价值.方法１６７例乳腺癌患者,术前采用经皮CEUS探查前哨淋巴结(SLN),评估SLN造影图像特征并对其进行导丝定位,与术中美蓝定位结果及病理结果对比,研究其诊断及定位效能.结果CEUS诊断SLN转移性敏感度为９１．０％、特异度为８８．０％、阳性预测值为８３．６％、阴性预测值为９３．６％、Kappa值为０．７８;若以SLN未见转移灶或腋窝低负荷状态为阴性标准,其诊断敏感度为９１．７％、特异度为９８．９％、阳性预测值为９１．７％、阴性预测值为９８．９％.对SLN定位显示:CEUS显示率、美蓝显示率、二者联合显示率分别为９４．５％(２９２/３０９)、９６．２％(３０１/３０９)、９９．１％(２０７/３０９).结论经皮CEUS对SLN定位及诊断效能好,一定程度上指导乳腺癌患者手术方式选择.关键词:经皮超声造影;乳腺癌;腋窝前哨淋巴结;诊断价值;定位中图分类号:R７３７．９文献标志码:A文章编号:１００９Ｇ８１９４(２０２３)０５－００４８－０４DOI:１０．１３７６４/j．cnki．lcsy．２０２３．０５．０１３ApplicationofPercutaneousContrastＧEnhancedUltrasoundinAxillarySentinelLymphNodeMetastasissinBreastCancerPatientsLIUTing,ZHENGWei,YUMeiＧqin,WANGJinＧling,NIEXiaoＧyan,XIONGHaiＧwei,XUZhiＧhui,ZHANGLiＧli(DepartmentofMedicalUltrasound,theFirstAffiliatedHospitalofNanchangUniversity,Nanchang３３０００６,China)ABSTRACT:ObjectiveToinvestigatethevalueofpercutaneouscontrastＧenhancedultrasound(CEUS)inthediagnosisandlocalizationofaxillarysentinellymphnode(SLN)metastasisinbreastcancerpatients．MethodsTheSLNfeatureswereevaluatedandwireＧlocalizationwasperＧformedin１６７breastcancerpatientsreceivingpercutaneousCEUSbeforeoperation．Thediagnosisandlocalizationefficiencieswereassessedthroughcomparingwiththeintraoperativemethylenebluelocalizationandpathologicalresults．ResultsThesensitivity,specificity,positivepredictivevalue,negativepredict...
