2010年第9期广东化工第37卷总第209期www.gdchem.com·35·超声波辅助提取广金钱草总黄酮的工艺研究王晓林，周媛媛，阴艳华(吉林化工学院化学与制药工程学院，吉林吉林132022)[摘要]为了充分合理利用广金钱草的自然资源，探索超声波辅助提取广金钱草总黄酮的工艺条件。以广金钱草提取干浸膏中总黄酮的含量为指标，采用单因素和正交试验确定超声波辅助提取广金钱草总黄酮的工艺条件。优化的的工艺条件为提取溶剂乙醇浓度为70%，超声时间为30min，料液比为1︰20，超声次数为3次。超声波辅助提取广金钱草总黄酮的工艺研究结果比较可靠，而且简单易行，具有提取温度低、时间短、含量高的优点。[关键词]广金钱草；总黄酮；超声提取；正交试验[中图分类号]TQ[文献标识码]A[文章编号]1007-1865(2010)09-0035-03StudyonExtractionProcessofTotalFlavonoidsfromHerbaDesmodiiStyracifoliiwithUltrasonicExtractionMethodWangXiaolin,ZhouYuanyuan,YinYanhua(SchoolofPharmaceuticalEngineeringandChemistry,JilinInstituteofChemicalTechnology,Jilin132022,China)Abstract:TostudytheoptimumextractionprocessoftotalflavonoidsinHerbaDesmodiiStyracifoliitousethiskindofnaturesourcefullyandrationally.Usingtheconcentrationoftotalflavonoidsasmainevaluatingindicators,theextractionprocesswasoptimizedwithsinglefactormethodandorthogonaldesign.TheoptimumconditionofextractingtotalflavonoidsinHerbaDesmodiiStyracifoliiwithultrtasonicmethodwereobtained,theconcentrationofethanol,theextractingtime,theratiobetweenrawmaterialandsolventandtheextractiontimeswere70%,30min,1:20,3timesrespectively.TheoptimumultrtasonicextractionprocessoftotalflavonoidsinHerbaDesmodiiStyracifoliiwashighefficientandthedeterminationmethodwaseasyandaccurate,whichcanbeusedforanalysisoftotalflavonoidsinthisherb.Keywords:herbadesmodiistyracifolii；totalflavonoids；ultrtasonicextraction；orthogonaldesign广金钱草(HerbaDesmodiiStyracifolii)为常用中药材，来源于豆科山蚂蝗属植物(Desmo-diumstyracifolium(Osbeck)Merr.)的干燥地上部分[1]，原植物为半灌木状草本，分布于广东、广西、福建、湖南等省区，广东为药材主产区，主要以其枝叶入药，具有清热祛湿、通淋、排石的功能，用于尿路感染、泌尿系结石、胆囊结石、肾炎浮肿等病症。...
