CACANCERJCLIN2019;0:1–231VOLUME0|NUMBER0|MONTH2019Abstract:ThenumberofcancersurvivorscontinuestoincreaseintheUnitedStatesbecauseofthegrowthandagingofthepopulationaswellasadvancesinearlydetectionandtreatment.Toassistthepublichealthcommunityinbetterservingtheseindividuals,theAmericanCancerSocietyandtheNationalCancerInstitutecollaborateevery3yearstoestimatecancerprevalenceintheUnitedStatesusingincidenceandsurvivaldatafromtheSurveillance,Epidemiology,andEndResultscancerregistries;vitalstatisticsfromtheCentersforDiseaseControlandPrevention’sNationalCenterforHealthStatistics;andpopulationprojectionsfromtheUSCensusBureau.CurrenttreatmentpatternsbasedoninformationintheNationalCancerDataBasearepresentedforthemostprevalentcancertypes.Cancer-relatedandtreatment-relatedshort-term,long-term,andlatehealtheffectsarealsobrieflydescribed.Morethan16.9millionAmericans(8.1millionmalesand8.8millionfemales)withahistoryofcancerwerealiveonJanuary1,2019;thisnumberisprojectedtoreachmorethan22.1millionbyJanuary1,2030basedonthegrowthandagingofthepopulationalone.The3mostprevalentcancersin2019areprostate(3,650,030),colonandrectum(776,120),andmela-nomaoftheskin(684,470)amongmales,andbreast(3,861,520),uterinecorpus(807,860),andcolonandrectum(768,650)amongfemales.Morethanone-half(56%)ofsurvivorswerediagnosedwithinthepast10years,andalmosttwo-thirds(64%)areaged65yearsorolder.Peoplewithahistoryofcancerhaveuniquemed-icalandpsychosocialneedsthatrequireproactiveassessmentandmanagementbyfollow-upcareproviders.Althoughtherearegrowingnumbersoftoolsthatcanassistpatients,caregivers,andcliniciansinnavigatingthevariousphasesofcan-cersurvivorship,furtherevidence-basedresourcesareneededtooptimizecare.CACancerJClin2019;0:1-23.©2019AmericanCancerSociety.Keywords:prevalence,statistics,survivorship,treatmentpatternsIntroductionThenumberofcancersurvivorscontinuestogrowintheUnitedStatesdespiteoveralldecliningage-standardizedincidenceratesinmenandstableratesinwomen.1Thisreflectsanincreasingnumberofnewcancerdiagnos...