2023年2月第30卷第2期阿司匹林联合他汀类药物治疗冠心病的效果及对患者心功能的影响章智1，芦舒2，王银1（1南阳市第三人民医院老年病科，河南南阳473000；2南阳市骨科医院药械科，河南南阳473000）【摘要】目的探讨阿司匹林联合他汀类药物治疗冠心病的效果及对患者心功能的影响。方法80例冠心病患者随机分为两组各40例，对照组给予阿司匹林治疗，研究组给予阿司匹林联合阿托伐他汀治疗，比较两组的临床疗效、心绞痛发作持续时间以及心功能指标。结果研究组的治疗总有效率为95．0％，高于对照组的75．0％（P＜0．05）。治疗后，研究组的心绞痛发作持续时间短于对照组，LVEDD、LVESD均低于对照组，LVEF高于对照组（P＜0．05）。结论阿司匹林联合他汀类药物治疗冠心病的效果显著，可有效缩短患者的心绞痛发作持续时间，改善患者的心功能。【关键词】冠心病；阿司匹林；他汀类药物；心功能指标中图分类号：R541.4文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.02.0223EffectofAspirinCombinedwithStatinsintheTreatmentofCoronaryHeartDiseaseandItsImpactonCardiacFunctionofPatients//ZHANGZhi1,LUShu2,WANGYin1(1DepartmentofGeriatrics,NanyangThirdPeople'sHospital,Nanyang473000,Chi-na;2DepartmentofMedicineandInstruments,NanyangOrthopaedicHospital,Nanyang473000,China)[Abstract]ObjectiveToexploretheeffectofaspirincombinedwithstatinsinthetreatmentofcoronaryheartdiseaseanditsimpactoncardiacfunctionofpatients.Methods80patientswithcoronaryheartdiseasewererandomlydividedintotwogroups,with40casesineachgroup.Thecontrolgroupwastreatedwithaspirin,andthestudygroupwastreatedwithaspirincombinedwithatorvastatin.Theclinicalefficacy,durationofanginapectorisandcardiacfunctionindicatorswerecomparedbetweenthetwogroups.ResultsThetotaleffectiverateoftreatmentinthestudygroupwas95.0%,higherthan75.0%inthecontrolgroup(P<0.05).Aftertreatment,thedurationofanginapectorisinthestudygroupwasshorterthanthatinthecontrolgroup,LVEDDandLVESDwerelowerthanthoseinthecontrolgroup,andLVEFwashigherthanthatinthecontrolgroup(P<0.05).ConclusionsAspirincombinedwithstatinsinthetreatmentofcoronaryheartdiseasehassignificanteffect,whichcaneffectivelyshortenthedurationofanginapectorisandimprovethec...
