http:/ropen.comFP病例报告Apr.2023,Vol.40,No.2DermatologyBulletin234皮肤科学通报2023年4月第40卷第2期5-氨基酮戊酸光动力疗法联合CO2点阵激光治疗女阴硬化性苔藓1例可方文宇，梁燕华[摘要]患者女,56岁，外阴白斑伴剧烈瘙痒10余年。专科查体：小阴唇、阴蒂萎缩，外阴境界清楚的瓷白色硬化萎缩斑。诊断：女阴硬化性苔藓。予以5-氨基酮戊酸光动力疗法（5-aminolevulinicacidphotodynam-ictherapy，ALA-PDT)联合CO,点阵激光治疗3次，瘙痒完全缓解，外阴白斑面积较前明显缩小，局部皮肤弹性恢复。[关键词]女阴硬化性苔藓;5-氨基酮戊酸光动力疗法;CO2点阵激光[中图分类号]R758.6[文献标识码]B[文章编号]2096-4382(2023)02-0234-035-AminolevulinicAcid-basedPhotodynamicTherapyCombinedwithCO,LatticeLaserintheTreatmentofVulvarLichenSclerosus:ACaseReportFANGWenyu,LIANGYanhua(DepartmentofDermatology,ShenzhenHospital,SouthernMedicalUniversity,Shenzhen518101,China[Correspondingauthor]LIANGYanhua,E-mail:liangdoctor@163.com[Abstract]A56-years-oldfemalepresentedwithleukoplakiawithseverepruritusonhervulvarformorethan10years.Physcialexaminationshowedatrophyofthelabiaminoraandclitoris,andaporcelain-whiteseleroticatrophicplaqueswithaclearvisibleboundaryofthevulva.Diagnosis:vulvalichensclerosus.After5-aminolevulinicacidphotodynamictherapyfollowingcarbondioxidelatticelaserfor3times,theitching[作者单位]南方医科大学深圳医院皮肤科，广东深圳518101[通信作者]梁燕华，E-mail：liangdoctor@163.com.235.皮肤科学通报2023年4月第40卷第2期wascompletelyrelieved,andtheareaofvulvarleukoplakiawassignificantlyreducedandthelocalskinelasticitywasrestored.[Keywords]Vulvarlichensclerosus;5-Aminolevulinicacidphotodynamictherapy;Carbondioxidelatticelaser1临床资料患者女，56岁，外阴白斑伴剧烈瘙痒10余年，多次外院就诊，曾外用卤米松乳膏、丙酸氟替卡松乳膏、他克莫司软膏等，用药时瘙痒能稍缓解，停药后再次反复，白斑面积逐渐扩大，瘙痒逐渐加重，遂就诊于本科。既往体健,否认慢性病史及传染病病史。皮肤科情况：小阴唇、阴蒂萎缩，大小阴唇无明显分界,外阴对称分布的瓷白色斑片，局部皮肤萎缩变薄，触之略硬，境界清楚，边缘略红。周身其余部位未见类似皮疹。皮损组织病理：表面角化过度，表皮...
