93综述NO.022023塑料科技PlasticsScienceandTechnology微塑料富集环境抗生素抗性基因的研究进展陈瑶1,2,夏子渊1,2,苟敏1,2*,孙照勇1,2,汤岳琴1,2(1.四川大学建筑与环境学院,四川成都610065;2.四川省环境保护有机废弃物资源化利用重点实验室,四川成都610065)摘要:微塑料已经在各种环境介质中被广泛检出,并且可能促进环境中抗生素抗性基因(ARGs)的富集与传播。文章从研究方法、富集效果、富集机制方面综述微塑料富集ARGs的研究进展,发现微塑料对多个环境中ARGs富集现象较明显,同时环境类型、微塑料暴露特征(种类、尺寸、暴露时间、与抗生素的联合作用)等因素对ARGs富集效果具有明显影响。微塑料从不同途径促进垂直基因转移与水平基因转移,实现ARGs富集。未来的研究应深入探讨微塑料对ARGs的富集机制,扩大环境研究范围,以进一步评估微塑料对ARGs的富集作用所引发的环境生态风险。关键词:微塑料;抗生素抗性基因;富集效果;富集机制中图分类号:X52;X832文献标识码:A文章编号:1005-3360(2023)02-0093-06DOI:10.15925/j.cnki.issn1005-3360.2023.02.019ResearchProgressonEnrichmentofAntibioticResistanceGenesinEnvironmentbyMicroplasticsCHENYao1,2,XIAZi-yuan1,2,GOUMin1,2*,SUNZhao-yong1,2,TANGYue-qin1,2(1.CollegeofArchitecture&Environment,SichuanUniversity,Chengdu610065,China;2.SichuanProvincialKeyLaboratoryofEnvironmentalProtectionOrganicWasteResourceUtilization,Chengdu610065,China)Abstract:Microplasticshavebeenwidelydetectedinavarietyofenvironmentalmedia.Microplasticsmaypromotetheenrichmentandspreadofantibioticresistancegenes(ARGs)intheenvironment.TheresearchprogressofARGsenrichmentbymicroplasticswasreviewedfromtheaspectsofresearchmethods,enrichmenteffectandenrichmentmechanism.ItisfoundthatmicroplasticshasobviousenrichmentofARGsinmultipleenvironments.Atthesametime,environmentaltypes,microplasticsexposurecharacteristics(type,size,exposuretime,combinedwithantibiotics)andotherfactorshavesignificanteffectsontheenrichmentofARGs.MicroplasticspromoteverticalgenetransferandhorizontalgenetransferfromdifferentwaystoachieveARGsenrichment.FutureresearchshouldfurtherexploretheenrichmentmechanismofmicroplasticsonARGsandexpandthescopeofenvir...