临床医学研究与实践2023年3月第8卷第9期表1两组患者的一般资料比较组别例数年龄(x�±s,岁)病程(x�±s,月)对照组148638.10±2.419.70±1.5195手术组26151138.60±3.909.70±3.801016类型(n)脑干肿瘤围脑干肿瘤性别(n)男女ClinicaleffectsofmicrosurgeryinthetreatmentofbrainstemtumorandaroundbrainstemtumorLINGNan,ZHANGXu*,ZHANGTong(theAffiliatedHospitalofXuzhouMedicalUniversity,Xuzhou221000,China)ABSTRACT:ObjectiveToexploretheclinicaleffectsofmicrosurgeryinthetreatmentofbrainstemtumorandaroundbrainstemtumor.MethodsFromOctober2017toSeptember2022,40patientswithbrainstemtumorandaroundbrainstemtumoradmittedinourhospitalweredividedintooperationgroup(26cases,microsurgeryscheme)andcontrolgroup(14cases,radiotherapyscheme)accordingtodifferenttreatmentmethods.Thetherapeuticeffectsofthetwogroupswerecompared.ResultsThetotaleffectiverateintreatmentoftheoperationgroupwashigherthanthatinthecontrolgroup(P<0.05).Aftertreatment,tumornecrosisfactor-α(TNF-α)andthymidinekinase1(TK1)levelsoftheoperationgroupwerelowerthanthoseofthecontrolgroup(P<0.05).ConclusionThemicrosurgeryonpatientswithbrainstemtumorandaroundbrainstemtumorhasasignificantclinicaleffect,whichisworthyofclinicalpromotion.KEYWORDS:brainstemtumor;aroundbrainstemtumor;microsurgery显微手术治疗脑干及围脑干肿瘤的临床效果凌南,张旭*,张桐(徐州医科大学附属医院,江苏徐州,221000)摘要:目的探讨显微手术治疗脑干及围脑干肿瘤的临床效果。方法将2017年10月至2022年9月我院收治的40例脑干及围脑干肿瘤患者按照治疗方式的不同分为手术组(26例,显微手术方案)和对照组(14例,放射治疗方案)。比较两组的治疗效果。结果手术组的治疗总有效率高于对照组(P<0.05)。治疗后,手术组的肿瘤坏死因子-α(TNF-α)、胸苷激酶1(TK1)水平低于对照组(P<0.05)。结论显微手术治疗脑干及围脑干区肿瘤患者的临床效果显著,值得临床推广。关键词:脑干肿瘤;围脑干肿瘤;显微手术中图分类号:R651.11文献标志码:A文章编号:2096-1413(2023)09-0030-04DOI:10.19347/j.cnki.2096-1413.202309009作者简介:凌南(1988—),男,主治医师,硕士。研究方向:颅脑解剖及脑肿瘤的显微外科治疗。*通讯作者:张旭...