113工艺技术《食品工业》2023年第44卷第4期三七葛精胶囊的制作工艺解成骏,周家明*,孙亚婷,马妮,赵爱,王朝梁文山学院(文山663099)摘要建立三七葛精胶囊这种对化学性肝损伤有辅助保护作用的保健食品的最佳制作工艺。采用水煎煮法进行提取试验,利用紫外分光光度法,通过正交试验法考察加水倍数、提取时间、提取次数3个因素对出膏率、三七总皂苷含量、葛根素含量的影响,进行提取工艺优化。考察胶囊内容物的吸湿率、休止角、制粒程度、堆密度,进行制粒工艺优化。结果表明:试验优化出的最佳提取工艺为加水倍数10倍,提取时间1.5h,提取次数3次;制粒工艺上选择微晶纤维素作为辅料添加,干膏粉和辅料配比4∶1,润湿剂为体积分数90%的乙醇,选用0号胶囊壳进行装填,胶囊符合质量标准检查。该配方制作工艺成本低,操作方便,合理可行。关键词三七葛精胶囊;提取工艺;制粒工艺PreparationProcessofSanqiGejingCapsuleXIEChengjun,ZHOUJiaming*,SUNYating,MANi,ZHAOAi,WANGChaoliangWenshanUniversity(Wenshan663099)AbstractPreparatethehealthfoodthatprotectedagainstchemicalliverinjurytoestablishthebestpreparationprocessofSanqiGejingcapsule.Theextractiontestwasperformedbywaterfryingmethod,usingorthogonalexperimentmethodtoexaminethewaterfactors,extractiontimeandextractiontimes,usingUVspectrophotometrytoexaminetheinfluenceofpasterate,Sanqitotalsaponincontentandpuerarincontent,andoptimizingtheextractionprocess.Checkthemoistureabsorptionrate,restingangle,granulationdegreeandstackingdensityofthecapsulecontent,andoptimizethegranulationprocess.Theresultshowedthatthebestextractionprocesswas10times,theextractiontimewas1.5h,andtheextractiontimeswere3times.Microcrystallinecellulosewasselectedasauxiliarymaterials,andtheratioofdrypastepowderandauxiliarymaterialswas4︰1;Thewettingagentwasethanolwitha90%volumefraction,selectingtheNo.0capsuleshellforfilling.Thepreparationprocessislowcost,convenientoperation,reasonableandfeasible.KeywordsSanqiGejingcapsule;extractionprocess;granulationprocess*通信作者;基金项目:云南省高校工程研究中心建设计划资助三七主要成分为三七总皂苷(PNS),其中人参皂苷Rb1、人参皂苷Rg1、三七皂苷R1为主要单体皂苷[1]。PNS可以改善人体肝脏血液循环,从而提...