*基金项目:国家自然科学基金项目(编号:81271190)**通信作者:黄声富,E-mail:shengfuh2006@whu.edu.cn青少年隐形矫治患者龈上菌斑龋病活跃性分析*岳圆1,程波1,黄声富2**(1.武汉大学中南医院口腔科湖北武汉430071;2.武汉大学口腔医院正畸科湖北武汉430071)[摘要]目的:检测青少年隐形矫治患者龈上菌斑致龋菌数目及其产酸耐酸能力变化,分析隐形矫治对青少年龋病活跃性的影响。方法:选取青少年隐形矫治患者14例,在矫治前、矫治3个月、6个月、12个月采集患者龈上菌斑样本;通过平板计数检测龈上菌斑中总厌氧菌、链球菌及变形链球菌的数目;将适当稀释度菌液加入不同pH值和不同葡萄糖浓度的BHI培养基中,检测其产酸耐酸能力。结果:与矫治前相比,在患者隐形矫治后3个月、6个月、12个月,厌氧菌数量及变形链球菌数量明显增加。菌斑产酸能力及耐酸能力均显著增强,且矫治6个月时最为显著。结论:隐形矫治器的佩戴使青少年患者龈上菌斑龋病活跃性增强,患龋风险增加。[关键词]隐形矫治;龈上菌斑;龋病活跃性;产酸性;耐酸性[中图分类号]R783.5R780.2[文献标识码]Adoi:10.3969/j.issn.1003-1634.2023.06.008Analysisofcariesactivityofsupragingivalplaqueinadolescentinvisibleorthodonticpatients.YUEYuan1,CHENGBo1,HUANGSheng-fu2**.1.DepartmentofStomatology,ZhongnanHospitalofWuhanUniversity,HubeiWuhan430071,China;2.DepartmentofOrthodontics,SchoolofStomatology,WuhanUniversity,HubeiWuhan430071,China.[Abstract]Objective:Thisstudyaimedtoinvestigatethealterationofthenumberofcariogenicbacteriaandacid-producingandacid-resistantabilityofsupragingivalplaqueinadolescentswithinvisibleorthodontictreatment,thusanalyzingtheeffectofinvisibleorthodontictreatmentoncariesactivityinadolescents.Methods:Fourteencasesofadolescentpatientswithinvisibleorthodontictreatmentwereselected.Thesupragingivalplaquesampleswerecollectedatthepre-treatment,3months,6monthsand12monthsaftertreatment.Thenumberoftotalanaerobicbacteria,streptococcusandStreptococcusmu-tansinsupragingivalplaquewasdetectedbycountingplates.Theappropriatedilutionofbacterialsolutionwasaddedtobrainheartinfusion(BHI)mediumwithdifferentpHanddifferentglucoseconcentrationstodetectitsacid-produc...