论著·临床研究doi:10.3969/j.issn.1671-8348.2023.08.012网络首发https://kns.cnki.net/kcms/detail//50.1097.R.20230208.1631.004.html(2023-02-09)脑室腹腔分流术后脑内出血3例报道并文献复习*赵丹旭1,2,刘春光1,2,钱东1,2,章顶立2,3,李宏廷2,3,张新宇2,徐学君2△(1.遵义医科大学研究生院,贵州遵义563000;2.四川省成都市第二人民医院神经外科610000;3.成都中医药大学研究生院610000)[摘要]目的探讨脑室腹腔分流术后脑内出血的原因及其发病机制。方法回顾性分析3例脑室腹腔分流术后脑内出血患者的临床资料,并结合相关文献进行复习。结果病例1在分流术后第1天发生早期脑内出血,由于出血量大,行颅内血肿清除术,病例2和3分别于分流术后第6、9天发生迟发性脑内出血,出血量较小行保守治疗。结论分流术后早期脑内出血可能是空心导管直接穿刺损伤微小血管及血管跨壁压增加所致,而迟发性脑内出血则可能是由于各种原因所致的脑组织脆弱性及导管对微小血管的延迟侵蚀作用造成。[关键词]脑室-腹腔分流术;脑室内出血;发病机制;文献复习[中图法分类号]R619[文献标识码]A[文章编号]1671-8348(2023)08-1177-05Intracerebralhemorrhagesecondarytoventriculoperitonealshunt:reportofthreecasesandliteraturereview*ZHAODanxu1,2,LIUChunguang1,2,QIANDong1,2,ZHANGDingli2,3,LIHongting2,3,ZHANGXinyu2,XUXuejun2△(1.GraduateSchoolofZunyiMedicalUniversity,Zunyi,Guizhou563000,China;2.DepartmentofNeurosurgery,ChengduSecondPeople’sHospital,Chengdu,Sichuan610000,China;3.GraduateSchoolofChengduUniversityofTraditionalChineseMedicine,Chengdu,Sichuan610000,China)[Abstract]ObjectiveToinvestigatethecausesandpathogenesisofintracerebralhemorrhagesecondarytoventriculoperitoneal(VP)shunt.MethodsTheclinicaldatain3casesofintracerebralhemorrhageafterVPshuntwereretrospectivelyanalyzedandthereviewwasperformedbycombiningwiththerelatedlitera-tures.ResultsThecase1developedearlyintracerebralhemorrhageon1daftertheshuntoperation.Thein-tracranialhematomaevacuationwasperformedduetothelargeamountofbleeding,thecase2andcase3de-velopedthedelayedintracerebralhemorrhageon6dand9daftershuntoperationrespectivelyandconductedtheconservativetreatmentduetothesmallamountofbleeding.ConclusionEarlyintracerebralhemorrhag...