国际精神病学杂志JOURNALOFINTERNATIONALPSYCHIATRY2023年第50卷第3期-437-◎临床研究◎ClinicalresearchMRI在高龄首发精神分裂症患者的诊断价值崔晶晶、王瑞举、孙岚、赵斐【摘要】目的探讨MRI诊断高龄首发精神分裂症患者的价值。方法将我院2020年9月~2022年7月期间收治的83例高龄首发精神分裂症患者为观察组,同期选取82例健康体检者作为对照组。比较两组脑白质病变参数、脑区病变参数以及脑灰质密度。结果观察组脑室前角间距、体部间距、第三脑室宽距、左右侧裂池宽距、大脑纵裂前半间距低于对照组,三角区域间距高于对照组(P<0.05);观察组左右侧侧脑室面积均大于对照组,距胼胝体下缘水平线长度、距大脑中线长度均长于对照组,穹隆脚中段部位厚度低于对照组,紧贴胼胝体处厚度高于对照组(P<0.05);观察组左右侧尾状核头、左侧小脑前叶、左侧小脑后叶、双侧丘脑灰质密度均低于对照组(P<0.05)。结论将MRI应用于高龄首发精神分裂症患者中,可通过检测其脑白质、脑区病变参数以及脑灰质密度数据变化,以初步评估患者脑部异常,为诊断提供一定依据。【关键词】磁共振成像;老年;首发精神分裂症;脑形态【中图分类号】R749.3【文献标识码】A【文章编号】1673-2952(2023)03-0437-04ThevalueofMRIinthediagnosisofsenilefirst-episodeschizophreniaCUIJingjing,WANGRuiju,SUNLan,etal.RadiologyDepartment,ZhengzhouNinthPeople'sHospital,Zhengzhou450053,China【Abstract】ObjectiveToexplorethevalueofMRIinthediagnosisofelderlyfirst-episodeschizophrenia.MethodsFromSeptember2020toJuly2022,83elderlyfirst-episodeschizophrenicsinourhospitalweretreatedastheobservationgroup,and82healthypeoplewereselectedasthecontrolgroupatthesametime.Theparametersofwhitematterlesions,brainarealesionsandgraymatterdensitywerecomparedbetweenthetwogroups.ResultsIntheobservationgroup,thedistancebetweentheanteriorhornandthebody,thewidthofthethirdventricle,thewidthoftheleftandrightsylviancisterns,andthedistancebetweentheanteriorhalfofthelongitudinalcerebralfissurewerelowerthanthoseinthecontrolgroup,andthedistancebetweenthetrigonalregionswashigherthanthatinthecontrolgroup(P<0.05).Theareaofleftandrightlateralventriclesintheobservationgroupwaslargerthanthatinthecontrolgroup,thele...