2023年2月国际神经病学神经外科学杂志Vol.50No.1第50卷第1期JournalofInternationalNeurologyandNeurosurgeryFeb.2023颅底硬膜缝合技术在内镜经鼻蝶入路鞍区肿瘤切除中的应用周律,王斌,王毅,吕波,单明,叶雷,高鹏,程宏伟安徽医科大学第一附属医院,安徽合肥230022摘要:目的探讨颅底硬膜缝合技术在内镜经鼻蝶入路切除鞍区肿瘤后颅底重建中的可行性和可靠性。方法分析安徽医科大学第一附属医院2019年1月—2021年7月在内镜下经鼻蝶入路切除鞍区肿瘤后采用颅底硬膜缝合技术处理的28例患者临床资料,并进行相关文献复习。结果28例患者均存在术中脑脊液漏(CSFL),参照Esposito分级法,术中发生1级CSFL14例,2级CSFL10例,3级CSFL4例。术中均采用了硬膜缝合技术修补鞍底,27例患者一期颅底重建成功,无术后CSFL发生,1例Rathkes囊肿患者术后出现CSFL,再次接受内镜下CSFL修补术,术后未再出现CSFL。结论结论颅底缝合硬膜,可以对颅底产生较大的支撑力,重建效果确切,值得临床应用。[国际神经病学神经外科学杂志,2023,50(1):9-14]关键词:脑脊液漏;硬膜缝合技术;神经内镜;脑肿瘤;经鼻蝶入路中图分类号:R651.13DOI:10.16636/j.cnki.jinn.1673-2642.2023.01.002Theapplicationofsellarduralsuturetechniqueinendoscopictranssphenoidalsellarregiontumorsresection.ZHOULü,WANGBin,WANGYi,LÜBo,SHANMing,YELei,GAOPeng,CHENGHongweiDepartmentofNeurosurgery,TheFirstAffiliatedHospitalofAnhuiMedicalUniversity,Hefei,Anhui230022,ChinaCorrespondingauthor:GAOPeng.Email:913476977@qq.com;CHENGHongwei.Email:chw001@163.comAbstract:ObjectiveTosummarizethefeasibilityandreliabilitysellarduralsuturetechniqueinendoscopictranssphe-noidalsellarregiontumorsresection.MethodsClinicaldataof28patientswithsellarregiontumorswhounderwentendo-scopictranssphenoidalsellarregiontumorsresectionfromJanuary2019toJuly2021wereanalyzedretrospectively.Andlit-eraturereviewwasalsocarriedout.ResultsAllthe28patientshadintraoperativeCSFleakage.AccordingtoKellygradingmethod,14casesofGrade1CSFleakage,10casesofGrade2CSFleakageand4casesofGrade3CSFleakageoccurredintraoperatively.Allcaseswereacceptedtheduralsuturetechniquetorepairthesaddlebase.Inthelast27patients,prima-ryskullbasereconstru...