第一页，共三十五页。2疗效总体评价肺部感染疗效腹部感染疗效中粒伴发热疗效退热时间(shíjiān)比较脑膜炎药物经济学第二页，共三十五页。3荟萃分析美平与亚胺培南治疗(zhìliáo)重度感染临床疗效EdwardsSJetal.CurrMedResOpin.2005May;21(5):785-94入选(rùxuǎn)27项临床研究，均为随机对照研究，且基于同等的剂量和给药方案亚胺培南n/N21/2550/5628/3660/74105/11131/3186/9081/8283/8879/82134/14848/50110/12267/8779/8249/6733/3939/4133/3944/4922/25220/27862/9135/4127/3061/7044/511985Studyorsub-categoryHara1992aHara1992bKumazawa1992aKumazawa1992bSartoretti1992Kanellakopoulou1993Brismar1995Cox1995Geroulanos1995Hamacher1995Morandini1995Nord1995Tallarigo1995Colardyn1996Vogel1996Garau1997Hartenauer1997Tonelli1997Bodman1999Pozzi1999Kuo2000Mészáros2000Verwaest2000Hou2001Song2001Hou2002Romanelli2002MEPMn/N23/2951/5927/3468/78105/11028/2897/9994/9579/8280/82147/15358/59122/12668/9080/8256/6630/3442/4333/3444/4823/2565/80Weight%1.423.221.713.876.565.665.465.034.968.553.267.024.284.963.051.932.511.93273RR(fixed)95%CI0.94(0.73-1.22)0.97(0.85-1.11)1.02(0.80-1.30)1.08(0.94-1.24)1.01(0.95-1.07)Notestimable1.03(0.97-1.08)1.00(0.97-1.03)1.02(0.96-1.09)1.01(0.96-1.07)1.06(1.00-1.13)1.02(0.96-1.09)1.07(1.00-1.15)0.98(0.83-1.16)1.01(0.96-1.07)1.16(0.97-1.39)1.04(0.87-1.25)1.03(0.94-1.12)1.15(0.99-1.33)1.02(0.90-1.16)1.05(0.87-1.26)1.03(0.91-1.16)1.13(0.94-1.36)1.03(0.87-1.22)1.04(0.89-1.21)1.03(0.92-1.16)1.00(0.86-1.17)104(101106)0.711.5RR(fixed)95%CI美平好亚胺培南好RR>1.00表明(biǎomíng)美平疗效优于亚胺培南/西司他丁总体疗效第三页，共三十五页。4入选27项临床研究，均为随机对照研究，且基于同等的剂量和给药方案1.05RR>1.00表明美平疗效优于亚胺培南/西司他丁总体疗效EdwardsSJetal.CurrMedResOpin.2005May;21(5):785-94第四页，共三十五页。5抗生素OR(95％CI）临床疗效细菌清除亚胺培南1.001.00美平1.52(1.23–1.86)1.45(1.15–1.80)头孢吡肟1.08(0.65–1.69)1.45(0.72–2.63)厄他培南0.83(0.57–1.15)0.76(0.32–1.52)哌拉西林/他唑巴坦0.76(0.55–1.00)0.83(0.47–1.35)EdwardsSJetal.CurrMedResOpin.2009Jan;25(1):251-61.应用MT...
