·综述·DOI:10.3969/j.issn.1001-5256.2023.03.030肝硬化患者肌肉减少症与肝性脑病的关系朱伊静,李伟,赵守松蚌埠医学院第一附属医院感染科,安徽蚌埠233000通信作者:李伟,liwei79722.student@sina.com(ORCID:0000-0002-1659-4910)摘要:肌肉减少症(简称肌少症)是肝硬化患者营养不良的表现形式之一。大多数研究表明,肌少症与显性肝性脑病导致肝硬化患者生活质量下降、临床预后不良甚至死亡等事件风险增加,但关于肌少症与轻微性肝性脑病之间的关系研究不多。通过对肌少症与肝性脑病的相关研究进展进行综述,指出改善患者的营养状况可预防轻微性肝性脑病发生,甚至降低显性肝性脑病的发生,从而改善患者预后,提高生存质量,降低死亡风险。关键词:肝硬化;肌减少症;肝性脑病Researchadvancesintheassociationbetweensarcopeniaandhepaticencephalopathyinpatientswithlivercir-rhosisZHUYijing,LIWei,ZHAOShousong.(DepartmentofInfectiousDiseases,TheFirstAffiliatedHospitalofBengbuMedicalCol-lege,Bengbu,Anhui233000,China)Correspondingauthor:LIWei,liwei79722.student@sina.com(ORCID:0000-0002-1659-4910)Abstract:Sarcopeniaisoneofthemanifestationsofmalnutritioninpatientswithlivercirrhosis.Moststudieshaveshownthatsarcopeniaisassociatedwithoverthepaticencephalopathy(OHE),leadingtoanincreasedriskofeventssuchasreducedqualityoflife,poorclinicalprognosis,andevendeathinpatientswithlivercirrhosis,buttherearefewstudiesontheassocia-tionbetweensarcopeniaandminimalhepaticencephalopathy(MHE).Thisarticlereviewstheresearchadvancesinsarcopeniaandhepaticencephalopathytoprovideareliablebasisforclinicaltreatment,anditispointedoutthatthenutritionalstatusofpatientscanbeimprovedtopreventMHEandevenreducetheonsetofOHE,therebyimprovingpatientprognosis,increasingqualityoflife,andreducingtheriskofdeath.Keywords:LiverCirrhosis;Sarcopenia;HepaticEncephalopathy1肝硬化患者肝性脑病(hepaticencephalopathy,HE)的分级肝硬化患者HE的发生率国内外报道不一,可能是因为临床医生对HE的诊断标准不统一以及对轻微性肝性脑病(minimalhepaticencephalopathy,MHE)的认知存在差异[1],其在整个肝硬化病程中发生率为30%~84%[2-3]。近年来,我国住院的肝硬化...