One-potsynthesisof(E)-diethyl2-styrylquinoline-3,4-di-carboxylatederivativesZhaoDi,LiuYanying,WangYang,LiYangChemistry(HuaxueTongbao),2023,86(5):589~597Asimpleandflexiblesynthesisofaseriesofnovel(E)-di-ethyl2-styrylquinoline-3,4-dicarboxylateswithgoodyieldshasbeenachieved,involvingone-potsequentialArbuzov/Horner-Wadsworth-Emmons(HWE)reactionsequenceusingdiethyl2-(bromomethyl)quinoline-3,4-dicarboxylateassubstrate.Synthesisandantitumoractivityof2-aryl-4-trifluorom-ethylquinazolinederivativesChenMingxiu,ChengSha,DaiXing,MengXueling,XuGuangcan,XuBixueChemistry(HuaxueTongbao),2023,86(5):598~606Aseriesofnovel2-aryl-4-trifluoromethylquinazolined-erivativesweresynthesizedstartingfrom5-chloro-2-nitro-benzoicacidbyhydrolysis,reduction,coupling,cyclization,trifluoromethyladdition,andeliminationreactions.Sometargetcompoundsshowedinhibitoryeffectonfivehumancancercelllines(PC3,LNCaP,K562,HeLaandA549)at5μmol·L-1.Anewstrategyfortheconstructionofphosphoylmethyl-enederivativescontainingindoleskeletonsFuJianping,XuChangjiang,XiaJun,HanXiaodanChemistry(HuaxueTongbao),2023,86(5):624~629Aseriesofphosphorylmethylenecompoundscontainingin-doleskeletonweresuccessfullyobtainedbyadditionreactionbetweenindoleenoylcompoundsanddiphenylphosphineox-ideinthepresenceofbase.Themethodexhibitsmanyad-vantagessuchaslowtemperature,highyield,rapidresponseetc.·315·http://www.hxtb.org化学通报2023年第86卷第5期
