CREDITS(TOPTOBOTTOM):(IMAGE)V.ALTOUNIAN/SCIENCE;(PHOTO)ISTOCK.COM/OZTURK20APRIL2018•VOL360ISSUE6386239SCIENCEsciencemag.org20APRIL2018•VOLUME360•ISSUE6386CONTENTS254Amolecularsuspectinkidneyfailure265WHISPERINGNEURONSFUELCORTICALHIGHWAYSSynapticcommunicationacceleratesneuronalmigrationinthedevelopingbrainByA.F.SchinderandG.M.Lanuza▶REPORTP.313267PARKINFUNCTIONINPARKINSON’SDISEASEModelsofParkin-mediatedubiquitinationlendinsightintotheroleofpathologicalmutationsByC.ArkinsonandH.Walden269IFTWODELETIONSDON’TSTOPGROWTH,TRYTHREETriplemutationsinyeastrevealbroadscopeofgeneticinteractionsByA.J.M.Walhout▶RESEARCHARTICLEP.283270AUNIFYINGCONCEPTINVASCULARHEALTHANDDISEASEInterventionstorestorebloodvesselstabilitycouldimprovehealthoutcomesByM.A.Schwartzetal.BOOKSETAL.272RECONSIDERINGTHENOBELPRIZEAfterduststymiesaquesttoconfirmcosmicinflation,aphysicistquestionsscience’smostprestigiousawardByP.Halpern274WIELDINGNEWGENOMICTOOLSWISELYTroublingtracesofbiocolonialismundermineanotherwiseeloquentsynthesisofancientgenomeresearchByM.C.ÁvilaArcosLETTERS276IVORYCRISIS:GROWINGNO-TRADECONSENSUSByN.Sekaretal.277IVORYCRISIS:ROLEOFBIOPRINTINGTECHNOLOGYByM.Lendaetal.277RESPONSEByD.Biggsetal.278INSURANCECOVERAGEFORGENOMICTESTSByK.A.Phillipsetal.253PROPOSALTORESCUEPOSTDOCSFROMLIMBODRAWSDARTSExpertpaneloffersmixofoldandnewideastohelpyoungbiomedicalresearchersbuildstablecareersByM.PriceFEATURE254OMENINTHEBLOODAproteinmarkerpredictshealthcrises—butcanitcausethem?ByS.HallINSIGHTSPOLICYFORUM260RISK-BASEDREBOOTFORGLOBALLABBIOSAFETYNewWHOguidancecouldexpandaccesstolabfacilitiesByK.Kojimaetal.PERSPECTIVES263PLANTRESPONSESTOCO2AREAQUESTIONOFTIMELong-termexperimentsshowunexpectedplantresponsestoelevatedCO2concentrationsByM.HovendenandP.Newton▶REPORTP.317264ONTHEQUESTFORTHESTRONGESTMATERIALSDiamondnanoneedleshavestrengthapproachingthetheoreticalmaximumByJ.LLorca▶REPORTP.300249NEWSINBRIEF244NewsataglanceINDEPTH247NASALANDERTOPROBEINTERIOROFMARSBylisteningformarsquakes,InSightwillmeasureRedPlane...