12FEBRUARY2016•VOL351ISSUE6274637SCIENCEsciencemag.org12FEBRUARY2016•VOLUME351•ISSUE6274CONTENTSNEWSINBRIEF642NewsataglanceINDEPTH645TRIUMPHFORGRAVITATIONALWAVEHUNTObservationmadewithnewlydetectableradiationclinchescaseforblackholesByA.Cho647BENDYBUGSINSPIREROBOTICISTSBees,wasps,andcockroachesarebuilttosurvivebashingandsqueezingByE.Pennisi648NEANDERTALGENESLINKEDTOMODERNDISEASESDNAinheritedfromourextinctcousinsboostsriskofdepression,otherdisordersByA.Gibbons▶REPORTP.737649RESEARCHCHIEFCUTSCLIMATESTUDIES,SETSNEWPRIORITIESCSIROtotrimstaffasitseekscloseralignmentwithindustryByL.Dayton650RECORDOZONEHOLEMAYOPENOVERARCTICINTHESPRINGUnusualpolarcoldproducescloudsthatcouldhelppushozonelossesbeyond2011mark,releasingextraUVradiationByE.Hand651ACRYSTALBALLFORCHEMICALSAFETYBycomparingnewchemicalstoknowncompounds,toxicologistsseekearlyhazardwarningByT.RabesandratanaFEATURE652AFTERTHEACCUSATIONAcomplexcaseofallegedsexualmisconductrattlesafieldandsignalsaculturalshiftByM.Balter664CLIMATECONFUSIONAMONGU.S.TEACHERSTeachers’knowledgeandvaluescanhinderclimateeducationByE.Plutzeretal.666COPPERCATALYSISINABLUELIGHTVisiblelight,copper,andaphosphineligandcombineforC-NbondformationatfullysubstitutedchiralcentersByM.F.Greaney▶REPORTP.681667ITTAKESTEAMWORKTOMODIFYCHROMATINTheorganizationofconstituentsinalargechromatin-modifyingcomplexrevealsspecificrolesByJ.L.Workman▶REPORTP.725668FINDINGANETHICALPATHFORWARDFORMITOCHONDRIALREPLACEMENTItisethicallypermissibletoinitiateclinicalinvestigationsofmitochondrialreplacementtechniquesinhumanssolongassignificantconditionsandrestrictionsareinplaceByA.B.Claiborneetal.670(TORC)INGUPPURINEBIOSYNTHESISAnenzymecomplexcoordinatesmetabolismandnucleotideproductiontofuelcellgrowthByE.H.MaandR.G.Jones▶REPORTSPP.728&733BOOKSETAL.672THESECRETWORLDINSIDEYOUR.DeSalleandS.Perkins,curators,reviewedbyV.Thompson673UNINFORMEDByA.Lupia,reviewedbyJ.Junn673THEHUMANFACEOFBIGDATAS.Smolan,directorLETTERS674THECRUSHINGWEIGHTOFURBANWASTEByH.Yangetal.674CHINA’SPARTIALE...