INSIGHTSLETTERS886INGENUITY:NEXTGEN’SVISION▶URBANPLANETSECTIONP.904PERSPECTIVES890CHANGINGOFTHEGUARDDNAnanostructuresmimicmembraneproteinsByS.Howorka891SUPERCONDUCTIVITYONTHEEDGEHybridcorrelatedsystemscouldrevealexoticquantumtransportbehaviorByN.Mason▶REPORTP.966892METHANE—MAKEITORBREAKITBiochemicaldataresolvethecontroversyoverhowmethanogenicarchaeaproducemethaneByT.J.LawtonandA.C.Rosenzweig▶RESEARCHARTICLEP.953INTRODUCTION904CitiesarethefutureNEWS906Riseofthecity908RootsoftheurbanmindByG.Miller912AplagueofratsByW.Cornwall916ChinarethinkscitiesByD.Normile918Vancouver’sgreendreamByK.R.WeissREVIEWS922City-integratedrenewableenergyforurbansustainabilityD.M.KammenandD.A.Sunter928EmergingsolutionstothewaterchallengesofanurbanizingworldT.A.Larsenetal.PERSPECTIVES934TransportsolutionsforcleanerairF.J.KellyandT.Zhu936TheecologicalfutureofcitiesM.J.McDonnellandI.MacGregor-Fors938Livingincities,naturallyT.HartigandP.H.KahnJr.940Meta-principlesfordevelopingsmart,sustainable,andhealthycitiesA.Ramaswamietal.943HiddenlinkagesbetweenurbanizationandfoodsystemsK.C.SetoandN.Ramankutty946BuildingfunctionalcitiesJ.V.Hendersonetal.ONTHECOVERMassivefogrollsintoDubai,UnitedArabEmirates.Ashosttomorethanhalfoftheworld’spopulation,citieshavefoot-printsthatreachwellbeyondtheirmunicipalboundaries.Efortsarenowunderwaytomakeurbanareasmoresustainableandefcient.Thechallengesandopportunitiesofoururbanplanetarehighlightedinaspecialsectionbeginningonpage904andonlineathttp://scim.ag/1Tb0WdZ.Photo:©SebastianOpitz/NovarcImages86820MAY2016•VOL352ISSUE6288sciencemag.orgSCIENCE20MAY2016•VOLUME352•ISSUE6288CONTENTS890Membrane-bendingDNAnanostructuresNEWSINBRIEF874NewsataglanceINDEPTH876TRACKINGHOWHUMANSEVOLVEINREALTIMEAnalysesofthousandsofsequencedgenomesshowchangesinaslittleasagenerationByE.Pennisi877‘CELLPAINTING’HIGHLIGHTSRESPONSESTODRUGSANDTOXINSMachinelearningcombinedwithmolecularpaintsallowsrapidscreeningofchangesincellshapeandfunctionByE.Pennisi878RESEARCHERSDECRYCONSENTPROPOSALU.S.wo...