·论著·通信作者:孙振晓,Email:szx.ywk@163.com加巴喷丁治疗奥氮平所致不宁腿综合征2例并文献复习孙振晓,赵林(临沂市精神卫生中心精神科,山东临沂276005)摘要:目的探讨加巴喷丁治疗奥氮平所致不宁腿综合征(restlesslegssyndrome,RLS)的有效性。方法回顾性分析2例加巴喷丁治疗奥氮平所致RLS患者的临床资料及诊疗经过,并对相关文献进行复习。结果2例精神分裂症患者均在应用奥氮平治疗期间出现夜间双下肢难以形容的不适,控制不住地想要活动双腿,并起床走动,否则周身不适,难以入睡,用手拍打下肢或下床走动可减轻不适。诊断奥氮平所致RLS,应用加巴喷丁治疗后取得较好疗效。结论加巴喷丁可用于奥氮平所致RLS的治疗。关键词:不宁腿综合征;精神分裂症;奥氮平;加巴喷丁中图分类号:R742.89文献标志码:A文章编号:1004-583X(2023)01-0068-03doi:10.3969/j.issn.1004-583X.2023.01.010Gabapentintreatmentinolanzapine-inducedrestlesslegssyndrome:TwocasesreportandliteraturereviewSunZhenxiao,ZhaoLinDepartmentofPsychiatry,LinyiMunicipalMentalHealthCenter,Linyi276005,ChinaCorrespondingauthor:SunZhenxiao,Email:szx.ywk@163.comABSTRACT:ObjectiveToexplorethetherapeuticefficacyofgabapentinonolanzapine-inducedrestlesslegssyndrome(RLS).MethodsTheclinicaldata,diagnosisandtreatmentof2casesofolanzapine-inducedRLStreatedwithgabapentinwereanalyzedretrospectively,andtherelatedliteratureswerereviewed.ResultsDuringthetreatmentwitholanzapine,twopatientswith...