张烨：CTA参数联合miR-21、miR-140-3p对冠状动脉狭窄的诊断价值CTA参数联合miR-21、miR-140-3p对冠状动脉狭窄的诊断价值张烨张烨陆军军医大学第二附属医院放射科，重庆400000摘要摘要目的分析螺旋CT造影术（CTangiography,CTA）参数联合miR-21、miR-140-3p对冠状动脉狭窄的诊断价值。方法选取2020年3月—2021年3月于陆军军医大学第二附属医院就诊的89例冠心病患者为观察组，均给予CTA、血清miR-21、miR-140-3p检查，详细记录检查结果，以冠状动脉造影术检查结果为金标准，评估CTA参数、血清miR-21、miR-140-3p联合在冠状动脉狭窄中的诊断价值。结果4种诊断方式对冠状动脉狭窄总检出结果比较，差异有统计学意义（P<0.05）；相比CTA参数（69.66%）、miR-21（49.43%）、miR-140-3p（50.56%）检查，3项联合检查冠状动脉狭窄检出率较高（89.88%），差异有统计学意义（χ2=4.265，P<0.05）。结论CTA参数、miR-21、miR-140-3p联合应用可有效检测冠状动脉狭窄情况，明确冠脉狭窄程度，为干预、预后评估提供重要参考。关键词关键词螺旋CT造影术；微小RNA-21；微小RNA-140-3p；冠状动脉狭窄中图分类号中图分类号R8181文献标志码文献标志码Adoi10.11966/j.issn.2095-994X.2022.08.11.04DiagnosticValueofCTAParametersCombinedwithmiR-21andmiR-140-3pforCoronaryArteryStenosisZHANGYeDepartmentofRadiology,theSecondAffiliatedHospitalofArmyMilitaryMedicalUniversity,Chongqing,400000ChinaAbstractObjectiveToanalyzethediagnosticvalueofspiralCTangiography(CTA)parameterscombinedwithmiR-21andmiR-140-3poncoronaryarterystenosis.Methods89patientswithcoronaryarterydiseasewhoattendedtotheSecondAffiliatedHospitalofArmyMilitaryMedicalUniversityfromMarch2020toMarch2021werecollectedastheobservationgroup.CTA,serummiR-21andmiR-140-3pweread⁃ministeredtoallpatients,andtheresultswererecordedindetailTakingtheresultsofcoronaryangiographyasthegoldstandard.Thediagnos⁃ticvalueofthecombinationofCTAparameters,serummiR-21andmiR-140-3pincoronaryarterystenosiswasevaluatedusingcoronaryan⁃giographyfindingsasthe"goldstandard".ResultsComparisonoftotaldetectionresultsoffourdiagnosticmethodsforcoronaryarterysteno⁃sis,andthedifferencewasstatisticallysignificant(P<0.05).ComparedwiththeexaminationofCTAparamete...
