popolysaccharide-inducedinflammatoryinjuryinCCD-18cocellsbytargetingGDF11throughtheTLR4/NF-κBandJNK/p38signalingpathways〔J〕.HistolHistopathol,2020;35(12):1473-81.6MalcomsonFC,WillisND,McCallumI,etal.Diet-associatedinflam-mationmodulatesinflammationandWNTsignalingintherectalmuco-sa,andtheresponsetosupplementationwithdietaryfiber〔J〕.CancerPrevRes(Phila),2020;14(3):337-46.7SolmazS,BehzadM,AliM,etal.miR-330regulatescolorectalcanceroncogenesisbytargetingBACH1〔J〕.AdvPharmBull,2020;10(3):444-51.8HongM,LiS,TanHY,etal.Currentstatusofherbalmedicinesinchronicliverdiseasetherapy:thebiologicaleffects,moleculartargetsandfutureprospects〔J〕.IntJMolSci,2015;16(12):28705-45.9QiJ,YuJ,LiY,etal.Alternatingconsumptionofbeta-glucanandquercetinreducesmortalityinmicewithcolorectalcancer〔J〕.FoodSciNutr,2019;7(10):3273-85.10GibelliniL,PintiM,NasiM,etal.A.Cossarizza,quercetinandcanc-erchemoprevention〔J〕.EvidBasedComplementAlternatMed,2011;2011:591356.11ChenX,DongXS,GaoHY,etal.SuppressionofHSP27increasestheantitumoreffectsofquercetininhumanleukemiaU937cells〔J〕.MolMedRep,2016;13(1):689-9612HocaM,BecerE,KabadayiH,etal.Theeffectofresveratrolandquercetinonepithelial-mesenchymaltransitioninpancreaticcancerstemcell〔J〕.NutrCancer,2020;72(7):1231-42.13ChenR,AlveroAB,SilasiDA,etal.Cancerstaketheirtoll-thefunc-tionandregulationoftoll-likereceptorsincancercells〔J〕.Onco-gene,2008;27:225-33.14SzajnikM,SzczepanskiMJ,CzystowskaM,etal.TLR4signalingin-ducedbylipopolysaccharideorpaclitaxelregulatestumorsurvivalandchemoresistanceinovariancancer〔J〕.Oncogene,2009;28:4353-63.15ZhuG,ChengZ,LinC,etal.MyD88regulatesLPS-inducedNF-κB/MAPKcytokinesandpromotesinflammationandmalignancyincolo-rectalcancercells〔J〕.CancerGenomicsProteomics,2019;16(6):409-19.16LiY,LinZ,ChenB,etal.Ezrin/NF-κBactivationregulatesepithe-lial-mesenchymaltransitioninducedbyEGFandpromotesmetastasisofcolorectalcancer〔J〕.BiomedPharmacother,...