Designation:F1416−96(Reapproved2014)StandardGuideforSelectionofTime-TemperatureIndicators1ThisstandardisissuedunderthefixeddesignationF1416;thenumberimmediatelyfollowingthedesignationindicatestheyearoforiginaladoptionor,inthecaseofrevision,theyearoflastrevision.Anumberinparenthesesindicatestheyearoflastreapproval.Asuperscriptepsilon(´)indicatesaneditorialchangesincethelastrevisionorreapproval.1.Scope1.1Thisguidecoversinformationontheselectionofcommerciallyavailabletime-temperatureindicators(TTIs)fornoninvasiveexternalpackageuseonperishableproducts,suchasfoodandpharmaceuticals.Whenattachedtothepackageofaperishableproduct,TTIsareusedtomeasurethecombinedtimeandtemperaturehistoryoftheproductinordertopredicttheremainingshelflifeoftheproductortosignaltheendofitsusableshelflife.Itistheresponsibilityoftheprocessoroftheperishableproducttodeterminetheshelflifeofaproductattheappropriatetemperaturesandtoconsultwiththeindicatormanufacturertoselecttheavailableindicatorwhichmostcloselymatchesthequalityoftheproductasafunctionoftimeandtemperature.NOTE1—Besidestime-temperatureindicator,TTIisalsoanabbrevia-tionfortime-temperaturemonitorandtime-temperatureintegrator.1.2Time-temperatureindicatorsmaybeintegratedintoaHazardAnalysisandCriticalControlPoint(HACCP)plan.Appropriateinstructionsshouldbeestablishedforhandlingproductsforwhicheithertheindicatorhassignaledtheendofusableshelflifeortheshelflifeoftheproductatitsnormalstoragetemperaturehasbeenreached.1.3Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappro-priatesafetyandhealthpracticesanddeterminetheapplica-bilityofregulatorylimitationspriortouse.2.Terminology2.1Definitions:2.1.1activationenergy—thequantitycommonlyusedtodescribethedependenceoftheshelflifeofaproduct(ortherateofareaction)ontemperature,asgivenbytheArrheniusrelationship.2.1.1.1Discussion—Thehighertheactivationenergy,themoretheshelflifeofaproductchangeswithtemperature.Ifthesh...
